Physician

Internal Medicine

Karl Seydel practices Internal Medicine. Karl B. Seydel is a published doctor. He published 42 publications, including: 'Epithelial cell-initiated inflammation plays a crucial role in early tissue damage in amebic infection of human intestine.'

Publications

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• Brain MRI of Children with Retinopathy-Negative Cerebral Malaria.
• Plasmodium falciparum transmission stages accumulate in the human bone marrow.
• Inferring developmental stage composition from gene expression in human malaria.
• NeuroInterp: A method for facilitating neuroimaging research on cerebral malaria.
• Histidine-Rich Protein 2 Plasma Levels Predict Progression to Cerebral Malaria in Malawian Children With Plasmodium falciparum Infection.
• MRI Findings in a Cohort of Brain Injured Survivors of Pediatric Cerebral Malaria.
• Acute brain MRI findings in 120 Malawian children with cerebral malaria: new insights into an ancient disease.
• Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle and Exhibits Therapeutic Potential to Treat Severe Malaria.
• A microfluidic system to study cytoadhesion of Plasmodium falciparum infected erythrocytes to primary brain microvascularendothelial cells.
• Elevated plasma von Willebrand factor and propeptide levels in malawian children with malaria.
• Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study.
• Blood coagulation, inflammation, and malaria.
• The distribution and intensity of parasite sequestration in comatose Malawian children.
• Plasmodium falciparum: characterization of a late asexual stage golgi protein containing both ankyrin and DHHC domains.
• Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.
• Detergent-resistant erythrocyte membrane rafts are modified by a Plasmodium falciparum infection.
• Severe malaria in children and pregnancy: an update and perspective.
• Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study.
• Recent Progress in Functional Genomic Research in Plasmodium falciparum.
• Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes.
• Anti-CD8 abrogates effect of anti-CD4-mediated islet allograft survival in rat model.
• Anti-CD4 mediates clonal anergy during transplantation tolerance induction.
• Induction of donor-specific unresponsiveness to cardiac allografts in rats by pretransplant anti-CD4 monoclonal antibody therapy.
• Selective T-cell depletion with Ox-38 anti-CD4 monoclonal antibody prevents cardiac allograft rejection in rats.
• Protection against amebic liver abscess formation in the severe combined immunodeficient mouse by human anti-amebic antibodies.
• SCID mice and the study of parasitic disease.
• Human intestinal epithelial cells produce proinflammatory cytokines in response to infection in a SCID mouse-human intestinal xenograft model of amebiasis.
• Identification of an epitope on the Entamoeba histolytica 170-kD lectin conferring antibody-mediated protection against invasive amebiasis.
• Neutrophils play a critical role in early resistance to amebic liver abscesses in severe combined immunodeficient mice.
• Cryptosporidium parvum infection of human intestinal xenografts in SCID mice induces production of human tumor necrosis factor alpha and interleukin-8.
• Entamoeba histolytica induces host cell death in amebic liver abscess by a non-Fas-dependent, non-tumor necrosis factor alpha-dependent pathway of apoptosis.
• Epithelial cell-initiated inflammation plays a crucial role in early tissue damage in amebic infection of human intestine.
• Innate immunity to amebic liver abscess is dependent on gamma interferon and nitric oxide in a murine model of disease.
• Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis.
• Shigella infection in a SCID mouse-human intestinal xenograft model: role for neutrophils in containing bacterial dissemination in human intestine.
• Ambulatory diagnoses-cluster statistics of patient visits at a clinic in the Amazon Region of Ecuador.
• Mild Plasmodium falciparum Malaria following an Episode of Severe Malaria Is Associated with Induction of the Interferon Pathway in Malawian Children.
• Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.
• Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection.
• Plasmodium falciparum gene expression measured directly from tissue during human infection.
• The systemic pathology of cerebral malaria in African children.

Schools

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• Washington Center School of Medicine

Doctors Specialties

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• Internal Medicine

Accepted Insurances

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