Professor, Medicine, University of Alabama School of Medicine
Internal Medicine
Dr. Victor J. Thannickal, MD
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Victor J. Thannickal practices Internal Medicine. He went to medical school at Oral Roberts University School of Medicine. He received awards:"Regional Top Doctor". Victor Thannickal is a published MD. He has 102 papers published. The most current publication "Upregulated expression of fibroblast growth factor (FGF) receptors by transforming growth factor-beta1 (TGF-beta1) mediates enhanced mitogenic responses to FGFs in cul..." He accepts all Medicare patients.
Publications
- Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?
- Oxidative Modifications of Protein Tyrosyl Residues are Increased in Plasma of Human Subjects with Interstitial Lung Disease.
- Blue journal conference. Aging and susceptibility to lung Disease.
- Noninvasive Imaging of Experimental Lung Fibrosis.
- The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.
- Extracorporeal Membrane Oxygenation for Acute Respiratory Failure in Adults: The Need for Pulmonary INTERMACS.
- Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence.
- Exposure to cigarette smoke impacts myeloid-derived regulatory cell function and exacerbates airway hyper-responsiveness.
- Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to Lung fibrosis.
- Negative regulation of NADPH oxidase-4 by hydrogen peroxide inducible clone-5.
- miR-27a Regulates Inflammatory Response of Macrophages by Targeting IL-10.
- Reversal of persistent fibrosis in aging by targeting nox4-nrf2 redox imbalance.
- The human long noncoding RNA, lnc-IL7R, regulates inflammatory response.
- Matrix Biology of Idiopathic Pulmonary Fibrosis: A Workshop Report of the National Heart, Lung, and Blood Institute.
- Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates Pulmonary fibrosis in mice.
- A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-β
- Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic Pulmonary fibrosis.
- NADPH Oxidases in Lung Health and Disease.
- Future Directions in Idiopathic Pulmonary Fibrosis Research: An NHLBI Workshop Report.
- Enhancement of antitumor immunity in Lung cancer by targeting myeloid-derived suppressor cell pathways.
- Mechanistic links between aging and Lung fibrosis.
- miR-145 regulates myofibroblast differentiation and Lung fibrosis.
- Vitronectin Inhibits Efferocytosis through Interactions with Apoptotic Cells as well as with Macrophages.
- Pleural Mesothelial Cell Differentiation and Invasion in Fibrogenic Lung Injury.
- HMGB1 PROMOTES NEUTROPHIL EXTRACELLULAR TRAP FORMATION THROUGH INTERACTIONS WITH TOLL LIKE RECEPTOR 4.
- Host responses in tissue repair and fibrosis.
- Vascular peroxidase 1 catalyzes the formation of hypohalous acids: Characterization of its substrate specificity and enzymatic properties.
- Neuronal Wiskott-Aldrich Syndrome Protein (N-WASP) Is Critical for Formation of α-Smooth Muscle Actin Filaments During Myofibroblast Differentiation.
- Update in diffuse parenchymal lung Disease 2011.
- Targeting NOX enzymes in Pulmonary fibrosis.
- Altered DNA Methylation Profile in Idiopathic Pulmonary Fibrosis.
- Mechanisms of Pulmonary fibrosis: role of activated myofibroblasts and NADPH oxidase.
- miR-31 is a negative regulator of fibrogenesis and Pulmonary fibrosis.
- Microbicidal Activity of VPO1 in Human Plasma via Generation of HOCl.
- Participation of miR-200 in Pulmonary Fibrosis.
- Relaxin Regulates Myofibroblast Contractility and Protects against Lung Fibrosis.
- A randomized trial of recombinant human granulocyte-macrophage colony-stimulating factor for patients with acute Lung injury.
- Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions.
- Oxidases and peroxidases in cardiovascular and lung Disease: New concepts in reactive oxygen species signaling.
- Cell Plasticity in Lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
- Nonresolving fibrotic disorders: idiopathic Pulmonary fibrosis as a paradigm of impaired tissue regeneration.
- Elevated levels of NO are localized to distal airways in asthma.
- Reversible differentiation of myofibroblasts by MyoD.
- MIR-29 is a Major Regulator of Genes Associated with Pulmonary Fibrosis.
- miR-21 mediates fibrogenic activation of Pulmonary fibroblasts and lung fibrosis.
- Caveolin-1 regulates dorsoventral patterning through direct interaction with beta-catenin in zebrafish.
- Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen acti...
- Challenges in translating preclinical studies to effective drug therapies in idiopathic Pulmonary fibrosis.
- Targeted injury of type II alveolar epithelial cells induces Pulmonary fibrosis.
- Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.
- Innovative approaches to the therapy of fibrosis.
- Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation.
- NOX enzymes and Pulmonary disease.
- NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to Lung injury.
- Oxygen in the evolution of complex life and the price we pay.
- Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human Lung endothelial cells.
- Update in diffuse parenchymal lung Disease 2008.
- Insulin-like growth factor-I receptor blockade improves outcome in mouse model of Lung injury.
- Idiopathic Pulmonary fibrosis: a disorder of lung regeneration?
- Transforming growth factor beta1 induces alphavbeta3 integrin expression in human Lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway.
- PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced Pulmonary fibrosis.
- Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis.
- PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.
- Lung cells from neonates show a mesenchymal stem cell phenotype.
- The myofibroblast: one function, multiple origins.
- Idiopathic Interstitial pneumonia: do community and academic physicians agree on diagnosis?
- Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: implications for treatment of fibrotic Diseases.
- Evidence for tissue-resident mesenchymal stem cells in human adult Lung from studies of transplanted allografts.
- Idiopathic Interstitial pneumonia: a clinicopathological perspective.
- Evolving concepts of apoptosis in idiopathic Pulmonary fibrosis.
- Differential protein expression profiling by iTRAQ-2DLC-MS/MS of Lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype.
- Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute Respiratory distress syndrome.
- Classification of Interstitial pneumonias: what do gene expression profiles tell us?
- Idiopathic Pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy.
- Platelet-derived growth factor-induced p42/44 mitogen-activated protein kinase activation and cellular growth is mediated by reactive oxygen species in the absence of ...
- Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts.
- CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury.
- Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury.
- Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection.
- STAT4 is a critical mediator of early innate immune responses against Pulmonary Klebsiella infection.
- Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands.
- Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent ind...
- Mechanisms of Pulmonary fibrosis.
- Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.
- Integrin alpha4beta1 regulates migration across basement membranes by Lung fibroblasts: a role for phosphatase and tensin homologue deleted on chromosome 10.
- Fibroblastic foci in usual interstitial pneumonia: idiopathic versus collagen vascular Disease.
- Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.
- The paradox of reactive oxygen species: injury, signaling, or both?
- SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts.
- Histone modifications in senescence-associated resistance to apoptosis by oxidative stress.
- Histone Deacetylase Inhibition Downregulates Collagen 3A1 in Fibrotic Lung Fibroblasts.
- Heritability of Pulmonary function estimated from pedigree and whole-genome markers.
- Oxidative protein cross-linking reactions involving L-tyrosine in transforming growth factor-beta1-stimulated fibroblasts.
- Reactive oxygen species in cell signaling.
- Ras-dependent and -independent regulation of reactive oxygen species by mitogenic growth factors and TGF-beta1.
- Transforming growth factor-beta 1-induced activation of the ERK pathway/activator protein-1 in human Lung fibroblasts requires the autocrine induction of basic fibrobl...
- Upregulated expression of fibroblast growth factor (FGF) receptors by transforming growth factor-beta1 (TGF-beta1) mediates enhanced mitogenic responses to FGFs in cul...
- Tyrosine phosphorylation regulates H2O2 production in Lung fibroblasts stimulated by transforming growth factor beta1.
- Therapeutic potential of an orally effective small molecule inhibitor of plasminogen activator inhibitor for asthma.
- The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to Lung injury.
- Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.
Schools
Oral Roberts University School Of Medicine
Procedures Preformed
- Bronchoscopy
- Thoracentesis
- Ventilation Management
Conditions Treated
- Acidosis
- Bronchiectasis
- Chronic Pulmonary Heart Diseases (incl. Pulmonary Hypertension)
- COPD (Chronic Obstructive Pulmonary Disease)
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Doctors Specialties
- Critical Care Medicine
- Pulmonology
- Internal Medicine
Accepted Insurances
Awards
- Regional Top Doctor
Education
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Tufts Medical Center -
Oral Roberts University School of Medicine
Hospital
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University of Alabama Hospital
Drug Facts
| NPI NUMBER | 1477635902 | |
| NPPES Provider LastName | THANNICKAL | |
| NPPES Provider FirstName | VICTOR | |
| NPPES Provider ZIPCode | 352332110 | |
| NPPES Provider State | AL | |
| Specialty Description | Pulmonary Disease | |
| Total Claim Count | 70.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1477635902 |
| Last Name Of The Provider | THANNICKAL |
| First Name Of The Provider | VICTOR |
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