Professor of Psychiatry and Behavioral Sciences, Professor of Neurology, Johns Hopkins University School of Medicine; Associate Program Director JHBMC GCRC, Director, Anxiety Disorders Program
Psychiatry
Dr. Una D. McCann, MD
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McCann is an expert in the field of Psychiatry. She went to medical school at Duke University School of Medicine. Duke University School of Medicine is a top medical college. Duke University School of Medicine is ranked 8 in research and 29 in primary care medicine McCann is a published doctor and has 100 publications published. The lastest was: 'Neural plasticity and emotional memory.' McCann is registered with Medicare.
Publications
- Single oral doses of (±) 3,4-methylenedioxymethamphetamine ('Ecstasy') produce lasting serotonergic deficits in non-human primates: relationship to plasma Drug and met...
- Studies of ({+/-})-3,4-Methylenedioxymethamphetamine (MDMA) Metabolism and Disposition in Rats and Mice: Relationship to Neuroprotection and Neurotoxicity Profile.
- Acute effects of zolpidem extended-release on cognitive performance and sleep in healthy males after repeated nightly use.
- Sleep apnea in young abstinent recreational MDMA ("ecstasy") consumers.
- Altered pain responses in abstinent (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users.
- Metabolism and Disposition of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") in Baboons After Oral Administration: Comparison to Humans Reveals Marked D...
- Peritraumatic heart rate and posttraumatic stress Disorder in patients with severe burns.
- Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity:...
- Sleep disturbance and the effects of extended-release zolpidem during cannabis withdrawal.
- Sleep apnea in young abstinent recreational MDMA ("ecstasy") consumers.
- Sleep deprivation differentially impairs cognitive performance in abstinent methylenedioxymethamphetamine ("Ecstasy") users.
- Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
- Direct comparison of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") disposition and metabolism in squirrel monkeys and humans.
- Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") and its Major metabolites in squirrel monkeys at plasma concentrations...
- Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users.
- The effect of catecholamine depletion by alpha-methyl-para-tyrosine on measures of cognitive performance and sleep in abstinent MDMA users.
- Quantitative positron emission tomography studies of the serotonin transporter in humans previously treated with the appetite suppressants fenfluramine or dexfenfluram...
- Performance characteristics of depression screening instruments in survivors of acute myocardial infarction: review of the evidence.
- The effects of sleep deprivation on pain inhibition and spontaneous pain in women.
- Pharmacokinetic profile of single and repeated oral doses of MDMA in squirrel monkeys: relationship to lasting effects on brain serotonin neurons.
- Plasma Drug concentrations and physiological measures in 'dance party' participants.
- Amphetamine treatment similar to that used in the treatment of adult attention-deficit/hyperactivity Disorder damages dopaminergic nerve endings in the striatum of adu...
- Quantitative PET studies of the serotonin transporter in MDMA users and controls using [11C]McN5652 and [11C]DASB.
- Depression following acute myocardial infarction: a prospective relationship with ongoing health and function.
- Individual variation in rapid eye movement sleep is associated with pain perception in healthy women: preliminary data.
- Identification and characterization of metallothionein-1 and -2 gene expression in the context of (+/-)3,4-methylenedioxymethamphetamine-induced toxicity to brain dopa...
- Amphetamine neurotoxicity: accomplishments and remaining challenges.
- Pentagastrin-induced sleep panic attacks: panic in the absence of elevated baseline arousal.
- Effect of glucoprivation on serotonin neurotoxicity induced by substituted amphetamines.
- Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy").
- Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.
- Altered prolactin response to M-chlorophenylpiperazine in monkeys previously treated with 3,4-methylenedioxymethamphetamine (MDMA) or fenfluramine.
- Changes in gene expression linked to methamphetamine-induced dopaminergic neurotoxicity.
- [Are convulsions necessary for the antiDepressive effect of electroconvulsive therapy: outcome of repeated transcranial magnetic stimulation].
- Attenuated response to m-CPP and to pentagastrin after repeated m-CPP in panic Disorder.
- Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance.
- Kindling versus quenching. Implications for the evolution and treatment of posttraumatic stress Disorder.
- Methylphenidate and brain dopamine neurotoxicity.
- Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated.
- Comparison of the daytime sleep and performance effects of zolpidem versus triazolam.
- Caffeine reversal of sleep deprivation effects on alertness and Mood.
- Loss of serotonin transporter protein after MDMA and other ring-substituted amphetamines.
- Relationship between temperature, dopaminergic neurotoxicity, and plasma Drug concentrations in methamphetamine-treated squirrel monkeys.
- Positron emission tomography of striatal serotonin transporters in Parkinson disease.
- Toward optimal health: the experts provide a current perspective on Anxiety in women. Interview by Jodi Godfrey Meisler.
- NREM sleep cerebral blood flow before and after behavior therapy for chronic primary insomnia: preliminary single photon emission computed tomography (SPECT) data.
- Sleep disturbance after mild traumatic brain injury: indicator of injury?
- Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects.
- Identifying the serotonin transporter signal in Western blot studies of the neurotoxic potential of MDMA and related Drugs.
- Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and Its 6-(N-Acetylcystein-S-yl) Conjugate.
- Repetitive TMS combined with exposure therapy for PTSD: a preliminary study.
- Approach-avoidance coping conflict in a sample of burn patients at risk for posttraumatic stress Disorder.
- Heating induces aggregation and decreases detection of serotonin transporter protein on western blots.
- Can doctors and nurses recognize depression in patients hospitalized with an acute myocardial infarction in the absence of formal screening?
- Post-myocardial infarction depression.
- Repetitive transcranial magnetic stimulation as a neuropsychiatric tool: present status and future potential.
- Neural plasticity and emotional memory.
- Memory impairment in abstinent MDMA ("Ecstasy") users.
- Adverse neuropsychiatric events associated with dexfenfluramine and fenfluramine.
- Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings.
- Neurotoxic effects of +/-fenfluramine and phenteramine, alone and in combination, on monoamine neurons in the mouse brain.
- Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35...
- Repetitive transcranial magnetic stimulation for posttraumatic stress Disorder.
- Brain dopamine neurotoxicity in baboons treated with doses of methamphetamine comparable to those recreationally abused by humans: evidence from [11C]WIN-35,428 positr...
- Effects of the 5-HT3 antagonist, ondansetron, on the behavioral and physiological effects of pentagastrin in patients with panic Disorder and social phobia.
- Brain serotonin neurotoxicity and primary pulmonary hypertension from fenfluramine and dexfenfluramine. A systematic review of the evidence.
- Effects of intravenous caffeine administered to healthy males during sleep.
- Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans.
- Neurotoxic amphetamine analogues: effects in monkeys and implications for humans.
- MDMA ("ecstasy") and panic Disorder: induction by a single dose.
- Sleep deprivation and impaired cognition. Possible role of brain catecholamines.
- Selective serotonin reuptake inhibitors dissociate fenfluramine's anorectic and neurotoxic effects: importance of dose, species and Drug.
- BallatroPhobia: when clowns aren't funny.
- Peptides and Anxiety: a dose-response evaluation of pentagastrin in healthy volunteers.
- A comparison of the effects of intravenous pentagastrin on patients with social phobia, panic Disorder and healthy controls.
- Prolactin response to fenfluramine is independent of serotonin release.
- Adverse reactions with 3,4-methylenedioxymethamphetamine (MDMA; ''ecstasy'').
- Algorithm for the treatment of panic Disorder with agoraphobia.
- The effects of L-dihydroxyphenylalanine on alertness and Mood in alpha-methyl-para-tyrosine-treated healthy humans. Further evidence for the role of catecholamines in ...
- Strategies for detecting subclinical monoamine depletions in humans.
- Reinforcing subjective effects of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: clinical evidence.
- Effects of catecholamine depletion on alertness and Mood in rested and sleep deprived normal volunteers.
- 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans.
- Persistent effects of (+/- )3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on human sleep.
- Fenfluramine''s appetite suppression and serotonin neurotoxicity are separable.
- Anatomical distribution of phenolic and tyrosyl ring iodothyronine deiodinases in the nervous system of normal and hypothyroid rats.
- Iodothyronine deiodination reaction types in several rat tissues: effects of age, thyroid status, and glucocorticoid treatment.
- What does the dexamethasone suppression test identify?
- Chronic pain and depression. II. Symptoms of Anxiety in chronic low back pain patients and their relationship to subtypes of depression.
- Chronic pain and depression. I. Classification of depression in chronic low back pain patients.
- Successful treatment of nonpurging bulimia nervosa with desipramine: a double-blind, placebo-controlled study.
- Acute dystonic reaction in normal humans caused by catecholamine depletion.
- Major metabolites of (+/-)3,4-methylenedioxyamphetamine (MDA) do not mediate its toxic effects on brain serotonin neurons.
- Lasting neuropsychiatric sequelae of (+-)methylenedioxymethamphetamine ('ecstasy') in recreational users.
- Panic attacks in healthy volunteers treated with a catecholamine synthesis inhibitor.
- Experimental studies on 3,4-methylenedioxymethamphetamine (MDA, "ecstasy") and its potential to damage brain serotonin neurons.
- Assessing long-term effects of MDMA (Ecstasy).
- Summary of a National Institute of Mental Health workshop: developing animal models of anxiety Disorders.
- A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity.
Schools
Duke University
Conditions Treated
- Adjustment Disorder
- Alcoholism (Alcohol Dependence)
- Anxiety
- Bipolar Disorder
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Doctors Specialties
- Psychosomatic Medicine
- Psychiatry
Accepted Insurances
Education
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Stanford University -
Duke University School of Medicine
Hospital
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Johns Hopkins Hospital -
Johns Hopkins Bayview Medical Center
Drug Facts
| NPI NUMBER | 1386693000 | |
| NPPES Provider LastName | MCCANN | |
| NPPES Provider FirstName | UNA | |
| NPPES Provider ZIPCode | 212242735 | |
| NPPES Provider State | MD | |
| Specialty Description | Psychiatry | |
| Total Claim Count | 72.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1386693000 |
| Last Name Of The Provider | MCCANN |
| First Name Of The Provider | UNA |
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