Physician
Psychiatry
Dr. Thomas A. Wehr, MD
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Thomas A. Wehr practices Psychiatry. He studied medicine at University of Louisville School of Medicine. University of Louisville School of Medicine has a rank of 83 in research and a 0 in primary care Thomas Wehr is also a published MD. He has 100 paper published. The most recent paper is: 5-HT agonist-induced phase-advances of the circadian pacemaker are diminished by chronic antidepressant drug treatment.
Publications
- A longer biological night in long sleepers than in short sleepers.
- Patients with seasonal affective disorder have lower odor detection thresholds than control subjects.
- Effect of diet on urinary MHPG excretion in depressed patients and normal control subjects.
- Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
- Phase advance of the circadian sleep-wake cycle as an antidepressant.
- Evidence that the pathophysiology of depression and the mechanism of action of antidepressant drugs both involve alterations in circadian rhythms.
- Age-related changes in sleep in depressed and normal subjects.
- Circadian rhythm mechanisms in affective illness and in antidepressant drug action.
- Diurnal mood variation and REM latency in depression.
- Longitudinal sleep EEG, temperature, and activity measurements across the menstrual cycle in patients with premenstrual depression and in age-matched controls.
- Can antidepressants cause mania and worsen the course of affective illness?
- Therapeutic effect of sleep deprivation in patients with premenstrual syndrome.
- Supersensitivity to light: possible trait marker for manic-depressive illness.
- Relationship between EEG sleep patterns and clinical improvement in depressed patients treated with sleep deprivation.
- Frequency analysis of the sleep EEG in depression.
- Diurnal variation: reliability of measurement and relationship to typical and atypical symptoms of depression.
- Rapid cycling.
- Clorgyline. A new treatment for patients with refractory rapid-cycling disorder.
- Can antidepressants induce rapid cycling?
- Rapid cycling in manic-depressives induced by tricyclic antidepressants.
- Unnecessary confusion about opposite findings in two studies of tricyclic treatment of bipolar illness.
- Thyroid abnormalities associated with rapid-cycling bipolar illness.
- Sleep deprivation: effects on circadian rhythms of rat brain neurotransmitter receptors.
- Chronic clorgyline treatment of Syrian hamsters: an analysis of effects on the circadian pacemaker.
- Is sleep deprivation useful in the treatment of depression?
- Melatonin and seasonal rhythms.
- Sleep-loss as a possible mediator of diverse causes of mania.
- Manipulations of sleep and phototherapy: nonpharmacological alternatives in the treatment of depression.
- Clorgyline-induced reduction in body temperature and its relationship to vigilance states in Syrian hamsters.
- Improvement of depression and triggering of mania by sleep deprivation.
- Sleep loss: a preventable cause of mania and other excited states.
- Influence of environmental factors on suicidal behavior.
- Diurnal variations of serotonin and dopamine levels in discrete brain regions of Syrian hamsters and their modification by chronic clorgyline treatment.
- Restoration of detectable melatonin after entrainment to a 24-hour schedule in a ''free-running'' man.
- Disruption of the activity-rest cycle by MAOI treatment: dependence on light and a secondary visual pathway to the circadian pacemaker.
- Increase of 5HT and VIP immunoreactivity within the hamster (Mesocricetus auratus) SCN during chronic MAOI treatment.
- Sleep reduction as a final common pathway in the genesis of mania.
- Manic-depressive patients may be supersensitive to light.
- Treatment of a patient with seasonal premenstrual syndrome.
- [Season-related forms of depression. I. Principles and clinical description of the syndrome].
- Environmental and behavioral influences on affective illness.
- Atenolol in premenstrual syndrome: a test of the melatonin hypothesis.
- Exposure to ultraviolet B radiation during phototherapy.
- Personality as a dimension of summer and winter depression.
- [Season-related forms of depression. II. Modification by phototherapy and biological results].
- Photoperiodism in humans and other primates: evidence and implications.
- 5-HT agonist-induced phase-advances of the circadian pacemaker are diminished by chronic antidepressant drug treatment.
- Decreased sensitivity to light of the photic entrainment pathway during chronic clorgyline and lithium treatments.
- Seasonal cycling in a bipolar patient.
- Antidepressant effects of sleep deprivation in bright and dim light.
- Melatonin secretion as a neurobiological "marker" and effects of light in humans.
- Bright artificial light treatment of a manic-depressive patient with a seasonal mood cycle.
- Antidepressant drug-induced hypothalamic cooling in Syrian hamsters.
- A brain-warming function for REM sleep.
- Twenty-four-hour profiles of body temperature and plasma TSH in bipolar patients during depression and during remission and in normal control subjects.
- Seasonal vulnerability to depression. Implications for etiology and treatment.
- Urinary 3-methoxy-4-hydroxyphenylglycol circadian rhythm. Early timing (phase-advance) in manic-depressives compared with normal subjects.
- The diurnal variation in plasma homovanillic acid level persists but the variation in 3-methoxy-4-hydroxyphenylglycol level is abolished under constant conditions.
- Cerebral glucose metabolism in patients with summer seasonal affective disorder.
- Nutritional and metabolic adaptations to prolonged sleep deprivation in the rat.
- 48-hour sleep-wake cycles in manic-depressive illness: naturalistic observations and sleep deprivation experiments.
- Effect of seasonal changes in daylength on human neuroendocrine function.
- A ''clock for all seasons'' in the human brain.
- A clinical trial of sleep deprivation in combination with antidepressant medication.
- Abnormal circadian rhythms of plasma melatonin and body temperature in the delayed sleep phase syndrome.
- Ultradian oscillations in cranial thermoregulation and electroencephalographic slow-wave activity during sleep are abnormal in humans with annual winter depression.
- Dynamics of electroencephalographic slow wave activity and body temperature during monophasic and biphasic human sleep.
- Seasonal affective disorder: a review of the syndrome and its public health implications.
- The dexamethasone suppression test in seasonal affective disorder.
- Seasonal affective disorder in children and adolescents.
- Antidepressant effects of light in seasonal affective disorder.
- Disturbances of appetite and weight regulation in seasonal affective disorder.
- Melatonin in seasonal affective disorder and phototherapy.
- Biological effects of morning-plus-evening bright light treatment of seasonal affective disorder.
- Eye versus skin phototherapy of seasonal affective disorder.
- Seasonal affective disorder & light: past, present and future.
- Circadian rhythm disturbances in manic-depressive illness.
- The effect of melatonin on normal sleep.
- Antidepressant effects of sleep deprivation and phototherapy.
- Findings from the Seasonal Pattern Assessment Questionnaire in patients with eating disorders and control subjects: effects of diagnosis and location.
- Treatment of seasonal affective disorder with light in the evening.
- The timing and duration of sleep in partial sleep deprivation therapy of depression.
- Sleep and circadian rhythms in affective patients isolated from external time cues.
- Serotonin and thermoregulation. Physiologic and pharmacologic aspects of control revealed by intravenous m-CPP in normal human subjects.
- Light therapy in patients with rapid cycling bipolar disorder: preliminary results.
- Potentiation of antidepressant medications by phase advance of the sleep-wake cycle.
- Seasonality and affective illness.
- [Effects of light in depressive syndromes].
- Nocturnal TSH and prolactin secretion during sleep deprivation and prediction of antidepressant response in patients with major depression.
- Fluoxetine decreases brain temperature and REM sleep in Syrian hamsters.
- Glucocorticoid replacement is permissive for rapid eye movement sleep and sleep consolidation in patients with adrenal insufficiency.
- The durations of human melatonin secretion and sleep respond to changes in daylength (photoperiod).
- Salivary and plasma measures of dim light melatonin onset (DLMO) in patients with rapid cycling bipolar disorder.
- Suppression of men's responses to seasonal changes in day length by modern artificial lighting.
- Treatment of rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep.
- Seasonal affective disorder and phototherapy.
- Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients.
- Contrasts between symptoms of summer depression and winter depression.
- Morning versus midday phototherapy of seasonal affective disorder.
Schools
University Of Louisville
Michael Reese Hospital and Med Center
Yale University
National Institutes Of Health Clinical Center
Doctors Specialties
- Psychiatry
Accepted Insurances
Education
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Yale University School of Medicine -
University of Louisville School of Medicine
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