Professor and Chair of Pathology and Laboratory Medicine, Medical University of South Carolina
Pathology
Dr. Steven L. Carroll, MD
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Steven L. Carroll works in the field of Pathology. He went to Baylor College of Medicine. Steven L. Carroll, MD is also published. He has 58 publications published. The lastest publication: "Expression of JE (monocyte chemoattractant protein-1) is induced by sciatic axotomy in wild type rodents but not in C57BL/Wld(s) mice.'
Publications
- STAT1 and NFkappaB Inhibitors Diminish Basal Interferon Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST cells.
- Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States.
- Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease: A Genome-Wide Association Study.
- Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines.
- Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling casca...
- Evaluation of the Safety and Biodistribution of M032, an Attenuated Herpes Simplex Virus Type 1 Expressing hIL-12, After Intracerebral Administration to Aotus Nonhuman...
- Evaluation of the Safety and Biodistribution of M032, an Attenuated HSV-1 Virus Expressing hIL-12, After Intracerebral Administration to Aotus Non-Human Primates.
- Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.
- Protector turns predator: Autophagic death via selective degradation of KRAS.
- 4-Hydroxytamoxifen Induces Autophagic Death through K-Ras Degradation.
- Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.
- Transgenic Mice Overexpressing Neuregulin-1 Model Neurofibroma-Malignant Peripheral Nerve Sheath Tumor Progression and Implicate Specific Chromosomal Copy Number Varia...
- Parsing out reality from genetically engineered mouse models of neurologic diseases.
- The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
- Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms.
- Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
- Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.
- Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents.
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
- Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.
- How does the Schwann cell lineage form tumors in NF1?
- Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.
- BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.
- Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.
- Neuregulin-1 enhances survival of human astrocytic glioma cells.
- Improved gene delivery into neuroglial cells using a fiber-modified adenovirus vector.
- Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor...
- Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons.
- Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.
- Ganglion-specific patterns of diabetes-modulated gene expression are established in prevertebral and paravertebral sympathetic ganglia prior to the development of neur...
- ErbB transmembrane tyrosine kinase receptors are expressed by sensory and motor neurons projecting into sciatic nerve.
- Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.
- Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line.
- Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
- Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve.
- Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease.
- BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells.
- The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally.
- Developmentally regulated expression of pleiotrophin, a novel heparin binding growth factor, in the nervous system of the rat.
- Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero.
- Liver fatty acid-binding protein: a marker for studying cellular differentiation in gut epithelial neoplasms.
- Clear cell neoplasms and pseudoneoplastic lesions of the central nervous system.
- Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls.
- Elements in the 5' flanking sequences of the mouse low-affinity NGF receptor gene direct appropriate CNS, but not PNS, expression in transgenic mice.
- Attenuation of experimental autoimmune demyelination in complement-deficient mice.
- Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia.
- Neuregulin-1beta modulates in vivo entorhinal-hippocampal synaptic transmission in adult rats.
- Expression of JE (monocyte chemoattractant protein-1) is induced by sciatic axotomy in wild type rodents but not in C57BL/Wld(s) mice.
- Neurotrophin sensitivity of prevertebral and paravertebral rat sympathetic autonomic ganglia.
- Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease.
- Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration.
- ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system.
- Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.
- Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis.
- A liquid chromatography mass spectrometry assay for determination of PD168393, a specific and irreversible inhibitor of erbB membrane tyrosine kinases, in rat serum.
- Constitutive activation of the neuregulin-1/erbB signaling pathway promotes the proliferation of a human peripheral neuroepithelioma cell line.
Schools
Baylor University
Barnes Jewish Hospital S Campus
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
- Blue Card PPO
- Dental Blue 100/200/300
- Cigna
- Kaiser Permanente
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Education
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Washington University - Barnes-Jewish Hospital -
Baylor College of Medicine
Hospital
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Birmingham Veterans Affairs Medical Center -
Children's of Alabama
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