Professor, Medicine, UCSD School of Medicine
Infectious Disease
Dr. Scott L. Letendre, MD
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Scott Letendre works in the field of Infectious Disease. He studied medicine at Georgetown University School of Medicine. Georgetown University School of Medicine is ranked 49/84 in Research/PrimaryCare. He over the years received 1 awards: "CMS Meaningful Use Stage 1 Certification". Doctor Scott L. Letendre, MD is a published doctor and has 97 publications published. The lastest was: 'HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders.' He accepts Medicare.
Publications
- HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders.
- Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection.
- Central nervous system penetration effectiveness of antiretroviral drugs and neuropsychological impairment in the Ontario HIV Treatment Network Cohort Study.
- Complement component 3 is associated with metabolic comorbidities in older HIV-positive adults.
- Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease.
- Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients.
- Methamphetamine Exposure Combined with HIV-1 Disease or gp120 Expression: Comparison of Learning and Executive Functions in Humans and Mice.
- Reply to Haddow et al.
- Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study.
- Antiretroviral therapy reduces neurodegeneration in HIV infection.
- Plasma and cerebrospinal fluid biomarkers predict cerebral injury in HIV-infected individuals on stable combination antiretroviral therapy.
- Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people.
- Individualized Texting for Adherence Building (iTAB): Improving Antiretroviral Dose Timing Among HIV-Infected Persons with Co-occurring Bipolar Disorder.
- Abdominal Obesity Contributes to Neurocognitive Impairment in HIV Infected Patients with Increased Inflammation and Immune Activation.
- Hepatitis B virus compartmentalization in the cerebrospinal fluid of HIV-infected patients.
- Persistent neurocognitive decline in a clinic sample of hepatitis C virus-infected persons receiving interferon and ribavirin treatment.
- Apathy is associated with white matter abnormalities in anterior, medial brain regions in persons with HIV infection.
- A history of alcohol dependence augments HIV-associated neurocognitive deficits in persons aged 60 and older.
- Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline.
- Detrimental impact of remote methamphetamine dependence on neurocognitive and everyday functioning in older but not younger HIV+ adults: evidence for a legacy effect?
- The veterans aging cohort study index is associated with concurrent risk for neurocognitive impairment.
- Absence of neurocognitive impairment in a large Chinese sample of HCV-infected injection drug users receiving methadone treatment.
- Randomized Trial of CNS-Targeted Antiretrovirals for HIV-Associated Neurocognitive Disorder.
- Real-world impact of neurocognitive deficits in acute and early HIV infection.
- "Frontal systems" behaviors in comorbid human immunodeficiency virus infection and methamphetamine dependency.
- Alterations in the Levels of Vesicular Trafficking Proteins Involved in HIV Replication in the Brains and CSF of Patients with HIV-associated Neurocognitive Disorders.
- A Concise Panel of Biomarkers Identifies Neurocognitive Functioning Changes in HIV-Infected Individuals.
- Dual-mixed HIV-1 coreceptor tropism and HIV-associated neurocognitive deficits.
- Increases in brain white matter abnormalities and subcortical gray matter are linked to CD4 recovery in HIV infection.
- Neurocognitive impairment in HIV-infected individuals with previous syphilis.
- Severe HIV-Associated CD8+ T-Cell Encephalitis: Is It the Tip of the Iceberg?
- Determination of Efavirenz in Human Dried Blood Spots by Reversed-phase High-performance Liquid Chromatography With UV Detection.
- Molecular and pathologic insights from latent HIV-1 infection in the human brain.
- Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection.
- Elevated sCD163 is a marker of neurocognitive impairment in HIV infection.
- Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer.
- Global NeuroAIDS Roundtable.
- Apolipoprotein E4 genotype does not increase risk of HIV-associated neurocognitive disorders.
- Etravirine in CSF is highly protein bound.
- Co-morbidities in persons infected with HIV: increased burden with older age and negative effects on health-related quality of life.
- Low prevalence of neurocognitive impairment in early diagnosed and managed HIV-infected persons.
- Risks and predictors of current suicidality in HIV-infected heroin users in treatment in Yunnan, China: A controlled study.
- Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
- Concurrent Classification Accuracy of the HIV Dementia Scale for HIV-associated Neurocognitive Disorders in the CHARTER Cohort.
- The Influence of HLA on HIV-Associated Neurocognitive Impairment in Anhui, China.
- Functional interactions of HIV-infection and methamphetamine dependence during motor programming.
- Prevalence and factors associated with sleep disturbances among early-treated HIV-infected persons.
- Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration.
- Genetic Variation in Iron Metabolism Is Associated with Neuropathic Pain and Pain Severity in HIV-Infected Patients on Antiretroviral Therapy.
- Biomarkers of HIV related central nervous system disease.
- Role of psychiatric medications as adjunct therapy in the treatment of HIV associated neurocognitive disorders.
- Impairments in fine-motor coordination and speed of information processing predict declines in everyday functioning in hepatitis C infection.
- Low atazanavir concentrations in cerebrospinal fluid.
- Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations.
- White matter tract injury and cognitive impairment in human immunodeficiency virus-infected individuals.
- Neurologic complications of HIV disease and their treatment.
- Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course.
- Lithium improves HIV-associated neurocognitive impairment.
- Effects of human immunodeficiency virus and methamphetamine on cerebral metabolites measured with magnetic resonance spectroscopy.
- High-dose lopinavir/ritonavir in highly treatment-experienced HIV-1 patients: efficacy, safety, and predictors of response.
- Is hepatitis C infection associated with increased risk of depression in persons with methamphetamine dependence?
- The role of cohort studies in drug development: clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the centra...
- Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance.
- HIV-associated deficits in action (verb) generation may reflect astrocytosis.
- Malaria diagnosis by a polymerase chain reaction-based assay using a pooling strategy.
- Incidence and nature of cognitive decline over 1 year among HIV-infected former plasma donors in China.
- Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy.
- Hepatitis C virus infection is associated with reduced white matter N-acetylaspartate in abstinent methamphetamine users.
- Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders.
- Population pharmacokinetics of abacavir in plasma and cerebrospinal fluid.
- The effects of hepatitis C, HIV, and methamphetamine dependence on neuropsychological performance: biological correlates of disease.
- Is the glass three-quarters full or one-quarter empty?
- Markers of macrophage activation and axonal injury are associated with prospective memory in HIV-1 disease.
- Frequency and predictors of self-reported prospective memory complaints in individuals infected with HIV.
- Implications of hepatitis C virus infection for behavioral symptoms and activities of daily living.
- Neurocognitive functioning in acute or early HIV infection.
- Successful cognitive aging in persons living with HIV infection.
- HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors.
- Efavirenz concentrations in CSF exceed IC50 for wild-type HIV.
- Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals.
- Clinical factors related to brain structure in HIV: the CHARTER study.
- Clinical variables identify seronegative HCV co-infection in HIV-infected individuals.
- Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder.
- Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers.
- Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system.
- Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies.
- Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy.
- Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling.
- CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy.
- Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change.
- Visual Function Assessment in Simulated Real-Life Situations in HIV-Infected Subjects.
- Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort.
- Pathogenesis of HIV in the central nervous system.
- Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: preliminary findings.
- Total raltegravir concentrations in cerebrospinal fluid exceed the 50-percent inhibitory concentration for wild-type HIV-1.
- Psychiatric context of human immunodeficiency virus infection among former plasma donors in rural China.
Schools
Georgetown University
Naval Hospital
Naval Med Center
Duke University
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Duke University Hospital -
Naval Medical Center -
Georgetown University School of Medicine
Hospital
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UC San Diego Health
Drug Facts
| NPI NUMBER | 1588696660 | |
| NPPES Provider LastName | LETENDRE | |
| NPPES Provider FirstName | SCOTT | |
| NPPES Provider ZIPCode | 921038201 | |
| NPPES Provider State | CA | |
| Specialty Description | Infectious Disease | |
| Total Claim Count | 16.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1588696660 |
| Last Name Of The Provider | LETENDRE |
| First Name Of The Provider | SCOTT |
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