University of Maryland
Pathology
Dr. Rudolph J. Castellani Jr., MD
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Rudolph J. Castellani Jr., MD works in the field of Pathology. He went to medical school at Wayne State University School of Medicine. Wayne State University School of Medicine is ranked 63/85 in Research/PrimaryCare. He has 5 awards "Harlan Firminger Award", "Mark A. Smith Award for Excellence in Neuroscience", "Alzheimer Medal", "Educator of the Year" and "Wall of Fame". Rudolph Castellani is a published physician. He has 73 papers published. The most current publication "Pathologic deposition of non-amyloid immunoglobulin in the brain leading to mass effect and neurological deficits." Rudolph J. Castellani Jr., MD is registered with Medicare and accepts Medicare payments.
Publications
- Pathologic deposition of non-amyloid immunoglobulin in the brain leading to mass effect and neurological deficits.
- Chondromyxoid fibroma invasion of the transverse-sigmoid sinus junction causing posterior fossa hemorrhage.
- Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes.
- Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.
- A novel PGC-1α isoform in brain localizes to mitochondria and associates with PINK1 and VDAC.
- Heterotopic Bone Formation About the Hip Undergoes Endochondral Ossification: A Rabbit Model.
- Cellular Alterations in Human Traumatic Brain Injury: Changes in Mitochondrial Morphology Reflect Regional Levels of Injury Severity.
- Oxidative damage to RNA in aging and neurodegenerative disorders.
- Class III gynecomastia in pediatric age: a new modified surgical treatment.
- Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich a...
- The blood-brain barrier in Alzheimer's disease: novel therapeutic targets and nanodrug delivery.
- Do beta-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?
- In vitro evidences of heparin's effects on embryo implantation and trophoblast development.
- Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
- Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
- The role of iron as a mediator of oxidative stress in Alzheimer disease.
- Mark A. Smith: neurocytochemistry innovator.
- Untangling the vascular web from Alzheimer disease and oxidative stress.
- Bi-layered collagen nano-structured membrane prototype (collagen matrix 10826((R)) ) for oral soft tissue regeneration: an "in vitro" study.
- Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
- Effect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL)-mediated inhibition of endometrial angiogenesis.
- Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing a...
- A novel perspective on tau in Alzheimer's disease.
- Iron: A Pathological Mediator of Alzheimer Disease?
- Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity.
- A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
- Mark A. Smith, 1965-2010: consummate student of pathogenesis.
- Frontiers in Alzheimer's disease therapeutics.
- Mark A. Smith: the scientist, the man.
- DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease.
- Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease.
- The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
- Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is 'too big to fail'.
- Obituary: Mark A Smith.
- CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson''s disease.
- Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis.
- Widespread distribution of reticulon-3 in various neurodegenerative diseases.
- Cocaine-induced intracerebral hemorrhage in a patient with cerebral amyloid angiopathy.
- Treatment advances in Alzheimer's disease based on the oxidative stress model.
- Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro.
- Alzheimer disease.
- Granulocytic sarcoma mimicking HSV encephalitis.
- Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
- Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
- Inherited neuroaxonal dystrophy in dogs causing lethal, fetal-onset motor system dysfunction and cerebellar hypoplasia.
- Antiphospholipid antibodies affect human endometrial angiogenesis.
- Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease.
- Antioxidant approaches for the treatment of Alzheimer's disease.
- Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective pl...
- Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.
- Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
- Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.
- Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics.
- Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure.
- Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease.
- RNA oxidation in Alzheimer disease and related neurodegenerative disorders.
- Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes.
- Molecular pathogenesis of Alzheimer's disease: Reductionist versus expansionist approaches.
- Sublethal RNA oxidation as a mechanism for neurodegenerative disease.
- Sudden unexpected death in lymphocytic hypophysitis.
- The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
- Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
- Proliferative verrucous leukoplakia: a potentially malignant disorder involving periodontal sites.
- Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.
- Sulfonylurea receptor 1 in the germinal matrix of premature infants.
- Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease.
- Pathology's new role: defining disease process and protective responses.
- Phosphorylated tau: toxic, protective, or none of the above.
- Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
- Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response.
- Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
- The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.
Schools
Wayne State University
University Of Michigan
Case Western Res University
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Select
- Amerigroup (Wellpoint)
- Great West Healthcare-Cigna PPO
- Commercial Insurance Company
- Emblem Health
- Geisinger Health Plan
- Maryland Physicians Care
- Medicare MCR
- United Healthcare
Awards
- Harlan Firminger Award
- Mark A. Smith Award for Excellence in Neuroscience
- Alzheimer Medal
- Educator of the Year
- Wall of Fame
Education
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Case Western Reserve University - University Hospitals -
Wayne State University School of Medicine -
University of Michigan Hospitals and Health Centers
Hospital
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University of Maryland Medical Center
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