Professor, Medicine, University of Alabama School of Medicine
Infectious Disease
Dr. Paul A. Goepfert, MD
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Paul Goepfert works in the field of Infectious Disease. He went to medical school at University of Alabama Medical Center. University of Alabama Medical Center is ranked 37/17 in Research/PrimaryCare. He over the years received 1 awards: "Elected Member". Paul A. Goepfert is also published. He has 56 publications published. The lastest publication: "Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083.
- Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.
- Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression.
- Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.
- Effects of atorvastatin and pravastatin on immune activation and T-cell function in antiretroviral therapy-suppressed HIV-1-infected patients.
- Human Immunodeficiency Virus Vaccines.
- Phase I/II Randomized Trial of Safety and Immunogenicity of LIPO-5 Alone, ALVAC-HIV (vCP1452) Alone, and ALVAC-HIV (vCP1452) Prime/LIPO-5 Boost in Healthy, HIV-1 Uninf...
- HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.
- Immune activation is associated with CD8 T-cell IL-21 production in HIV-1-infected individuals.
- Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway.
- Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles.
- Characterization of T-cell responses to cryptic epitopes in recipients of a noncodon-optimized HIV-1 vaccine.
- HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells.
- HIV-specific CD8+ T cells from elite controllers are primed for survival.
- Hormonal Contraception and HIV-1 Infection: Medroxyprogesterone Acetate Suppresses Innate and Adaptive Immune Mechanisms.
- Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
- Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women.
- Cumulative impact of host and viral factors on HIV-1 viral-load control during early infection.
- Host Factor Transcriptional Regulation Contributes to Preferential Expression of HIV Type 1 in IL-4-Producing CD4 T Cells.
- Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated.
- Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections.
- Interleukin-2 Production by Polyfunctional HIV-1-Specific CD8 T-Cells is Associated with Enhanced Viral Suppression.
- Glycoprotein B vaccine is capable of boosting both antibody and CD4 T-cell responses to cytomegalovirus in chronically infected women.
- CD8 T-cell proliferative capacity is compromised in primary HIV-1 infection.
- Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers.
- Menstrual Blood as a Potential Source of Endometrial Derived CD3+ T Cells.
- Enhanced induction of HIV-specific cytotoxic T lymphocytes by dendritic cell-targeted delivery of SOCS-1 siRNA.
- Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.
- CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.
- Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
- Multifunctional T-cell characteristics induced by a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine regimen given to healthy adults are ...
- Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees.
- Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.
- Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients.
- Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophil...
- Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid ...
- Functionally competent antigen-specific CD127(hi) memory CD8+ T cells are preserved only in HIV-infected individuals receiving early treatment.
- Evaluation of cellular immune responses in subjects chronically infected with HIV type 1.
- HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells.
- HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently.
- Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help.
- Breast milk-derived antigen-specific CD8+ T cells: an extralymphoid effector memory cell population in humans.
- Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individuals.
- T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles.
- Cross-reactive CD8+ T cell epitopes identified in US adolescent minorities.
- Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunization.
- Foamy virus envelope glycoprotein is sufficient for particle budding and release.
- Making sense of the HIV immune response.
- Human immunodeficiency virus-specific CD8(+) T cells in human breast milk.
- Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma.
- Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4.
- Characterization of Programmed Death-1 Homologue-1 (PD-1H) Expression and Function in Normal and HIV Infected Individuals.
- KIR2DS4 Promotes HIV-1 Pathogenesis: New Evidence from Analyses of Immunogenetic Data and Natural Killer Cell Function.
- Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis.
- Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing.
Schools
Baylor College Of Medicine
Birmingham Mc
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
Education
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University of Alabama Medical Center -
Baylor College of Medicine
Hospital
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University of Alabama Hospital -
Birmingham Veterans Affairs Medical Center
Drug Facts
| NPI NUMBER | 1366470718 | |
| NPPES Provider LastName | GOEPFERT | |
| NPPES Provider FirstName | PAUL | |
| NPPES Provider ZIPCode | 35233 | |
| NPPES Provider State | AL | |
| Specialty Description | Infectious Disease | |
| Total Claim Count | 1499.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 30.0 | |
| Percent Opioid Claims | 2.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1366470718 |
| Last Name Of The Provider | GOEPFERT |
| First Name Of The Provider | PAUL |
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