Professor of Internal Medicine Referal practice University Hospital
Nephrology
Dr. Orson W. Moe, MD
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Orson works in the field of Nephrology. He received awards:"CMS Meaningful Use Stage 1 Certification" and "Elected Member". Orson is also published. He has 101 publications published. The lastest publication: "Nanoparticle Facilitated Inhalational Delivery of Erythropoietin Receptor cDNA Protects Against Hyperoxic Lung Injury.' He is registered with Medicare and accepts Medicare payments.
Publications
- Nanoparticle Facilitated Inhalational Delivery of Erythropoietin Receptor cDNA Protects Against Hyperoxic Lung Injury.
- Fibroblast growth factor 23 and Acute kidney injury.
- Relationship Between Serum Uric Acid and Bone Mineral Density in the General Population and in Rats With Experimental Hyperuricemia.
- α-Klotho protects against oxidative damage in pulmonary epithelia.
- Incomplete Distal Renal Tubular Acidosis from a Heterozygous Mutation of the V-ATPase B1 Subunit.
- αKlotho and vascular calcification: an evolving paradigm.
- Fibroblast growth factor 23 and uremic vascular calcification: is it time to escalate from biomarker status to pathogenic agent?
- Klotho has dual protective effects on cisplatin-induced Acute kidney injury.
- Effects of Sex and Postmenopausal Estrogen Use on Serum Phosphorus Levels: A Cross-sectional Study of the National Health and Nutrition Examination Survey (NHANES) 200...
- Renal ammonium excretion after an Acute acid load: Blunted response in uric acid stone formers but not in patients with type 2 diabetes.
- SLC26A6 and NaDC-1 Transporters Interact to Regulate Oxalate and Citrate Homeostasis.
- Human-induced pluripotent stem cell-derived cardiomyocytes for studies of cardiac ion transporters.
- Clinical assessment of phosphorus status, balance and renal handling in normal individuals and in patients with chronic Kidney disease.
- The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
- Renal and extraRenal actions of klotho.
- Chronic Regulation of the Renal Na+/H+ Exchanger NHE3 by Dopamine: Translational and Post-Translational Mechanisms.
- Adiponectin promotes functional recovery after podocyte ablation.
- Proximal tubule Na+/H+ exchanger activity in adult NHE8-/-, NHE3-/-, and NHE3-/-/NHE8-/- mice.
- Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic Kidney disease fed a high phosphate diet.
- Renal transport of uric Acid: evolving concepts and uncertainties.
- Subclinical Celiac Disease and Crystal-Induced Kidney Disease Following Kidney Transplant.
- Klotho as a potential biomarker and therapy for Acute kidney injury.
- Metabolic syndrome and the risk of Calcium stones.
- Calcineurin Homologous Protein: A multi-functional Ca2+-binding protein family.
- Association of Urinary Sodium/Potassium Ratio With Blood Pressure: Sex and Racial Differences.
- FGF23 induces left ventricular hypertrophy.
- Hypercalciuria Associated With High Dietary Protein Intake Is Not Due to Acid Load.
- The reduction of Na/H exchanger-3 protein and transcript expression in Acute ischemia-reperfusion injury is mediated by extractable tissue factor(s).
- Defining hypercalciuria in nephrolithiasis.
- Comparison of Insulin Action on Glucose versus Potassium Uptake in Humans.
- Klotho: a novel regulator of Calcium and phosphorus homeostasis.
- Pharmacotherapy of urolithiasis: evidence from clinical trials.
- Nephrolithiasis-associated bone Disease: pathogenesis and treatment options.
- Klotho deficiency causes vascular calcification in chronic Kidney disease.
- Nephrolithiasis in topiramate users.
- Klotho deficiency is an early biomarker of Renal ischemia-reperfusion injury and its replacement is protective.
- Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian Kidney.
- Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the Renal proximal tubule.
- Metabolic basis for low urine pH in type 2 Diabetes.
- Posing the question again: does Chronic uric acid nephropathy exist?
- Acute Regulation of Renal Na+/H+ Exchanger NHE3 by Dopamine: Role of Protein Phosphatase 2A.
- Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
- Harnessing transporters to clear uremic toxins.
- Biochemical and histological assessment of alkali therapy during high animal protein intake in the rat.
- Reduction of Renal triglyceride accumulation: effects on proximal tubule Na+/H+ exchange and urinary acidification.
- Renal phosphate wasting due to tumor-induced osteomalacia: a frequently delayed diagnosis.
- Inhibition of osteoclast formation and function by bicarbonate: role of soluble adenylyl cyclase.
- The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation.
- GABARAP deficiency modulates expression of NaPi-IIa in Renal brush-border membranes.
- PiT-2 coming out of the pits.
- Comparison of semi-empirical and computer derived methods for estimating urinary saturation of brushite.
- Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells.
- Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models With 2Na/2H stoichiometry.
- Mechanism of urinary Calcium regulation by urinary magnesium and pH.
- Characterization of the sodium/hydrogen exchanger NHA2.
- Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yea...
- Glucocorticoid-mediated Hypertension: does the vascular smooth muscle hold all the answers?
- Effect of Renal lipid accumulation on proximal tubule Na+/H+ exchange and ammonium secretion.
- Synergistic upregulation of erythropoietin receptor (EPO-R) expression by sense and antisense EPO-R transcripts in the canine lung.
- Low urine pH: a novel feature of the metabolic syndrome.
- Characterization of Na+/H+ exchanger NHE8 in cultured Renal epithelial cells.
- When EGF is offside, Magnesium is wasted.
- Postpneumonectomy lung expansion elicits hypoxia-inducible factor-1alpha signaling.
- Ontogeny of NHE8 in the rat proximal tubule.
- A sperm-specific Na+/H+ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC).
- Characterization of the regulation of Renal Na+/H+ exchanger NHE3 by insulin.
- Biochemical and stone-risk profiles With topiramate treatment.
- An unusual case of urticaria and nephrotic syndrome.
- Na+/H+ exchangers in Renal regulation of acid-base balance.
- Regulated expression of hypoxia-inducible factors during postnatal and postpneumonectomy lung growth.
- Urine composition in type 2 Diabetes: predisposition to uric acid nephrolithiasis.
- Regulation of fibroblast growth factor-23 signaling by klotho.
- Shank2 associates With and regulates Na+/H+ exchanger 3.
- Glucocorticoids Acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.
- Cloning and characterization of the human soluble adenylyl cyclase.
- Physicochemical metabolic characteristics for Calcium oxalate stone formation in patients with gouty diathesis.
- Activation of dopamine D1-like receptors induces Acute internalization of the renal Na+/phosphate cotransporter NaPi-IIa in mouse kidney and OK cells.
- Genetic hypercalciuria.
- Phosphatonin washout in Hyp mice proximal tubules: evidence for posttranscriptional regulation.
- Upregulation of erythropoietin receptor during postnatal and postpneumonectomy lung growth.
- Rapid Communication: relative effect of urinary Calcium and oxalate on saturation of Calcium oxalate.
- Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods.
- The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in Renal cortex.
- OKP cells express the Na-dicarboxylate cotransporter NaDC-1.
- Recurrent Calcium nephrolithiasis associated with primary aldosteronism.
- The metabolic syndrome and uric acid nephrolithiasis: novel features of Renal manifestation of insulin resistance.
- Acute regulation of Na/H exchanger NHE3 by adenosine A(1) receptors is mediated by calcineurin homologous protein.
- Albumin regulates the Na+/H+ exchanger 3 in OKP cells.
- Effect of high protein diet on stone-forming propensity and bone loss in rats.
- Dopamine Acutely decreases apical membrane Na/H exchanger NHE3 protein in mouse renal proximal tubule.
- Scaffolds: Orchestrating proteins to achieve concerted function.
- Long-term combined treatment with thiazide and potassium citrate in nephrolithiasis does not lead to hypokalemia or hypochloremic metabolic Alkalosis.
- Pathophysiology of uric acid nephrolithiasis.
- Bicarbonate reabsorption and NHE-3 expression: abundance and activity are increased in Henle's loop of remnant rats.
- Etiological role of estrogen status in Renal stone formation.
- Expression of epidermal growth factor and surfactant proteins during postnatal and compensatory lung growth.
- Insulin activates Na(+)/H(+) exchanger 3: biphasic response and glucocorticoid dependence.
- Collapsing glomerulopathy: a cause of noncardiogenic pulmonary edema.
- Pathophysiologic basis for normouricosuric uric acid nephrolithiasis.
- Role of c-SRC and ERK in acid-induced activation of NHE3.
Schools
University Of Toronto Faculty Of Medicine
St Michaels Hospital University Toronto
Toronto Genl Hospital University Toronto
University Toronto Nephr Program
Procedures Preformed
- Hemodialysis
Conditions Treated
- Acidosis
- Acute Kidney Failure
- Alkalosis
- Calcium Metabolism Disorders
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Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Elected Member
Education
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University of Toronto Faculty of Medicine -
University of Toronto
Hospital
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University of Texas Southwestern Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1619946191 |
| Last Name Of The Provider | MOE |
| First Name Of The Provider | ORSON |
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