Professor of Pediatrics, UCSF
Allergy & Immunology
Dr. Morton J. Cowan, MD
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Morton J. Cowan is an expert in the field of Allergy & Immunology. He attended Perelman School of Medicine at the University of Pennsylvania. He has 3 awards "America's Top Doctors", "America's Top Doctors for Cancer" and "Super Doctor". Morton J. Cowan, MD is also a published doctor. He has 63 paper published. The most recent paper is: Evaluation of Pre-Hematopoietic Cell Transplantation (HCT) Brain MRI and Neurologic Complications of Pediatric Patients Undergoing HCT for Hematologic Malignancies.
Publications
- Radiation-sensitive severe Combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation-what to do?
- Chimerism-based pre-emptive immunotherapy with fast withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic stem cell transplantation for pedia...
- Role of Transgene Regulation in Ex Vivo Lentiviral Correction of Artemis Deficiency.
- Successful newborn screening for SCID in the Navajo Nation.
- Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency.
- Combined Immunodeficiency Due to MALT1 Mutations, Treated by Hematopoietic Cell Transplantation.
- Stem cell transplantation for primary immunoDeficiency diseases: the North American experience.
- Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of seve...
- Population Pharmacokinetics of Busulfan in Pediatric and Young Adult Patients Undergoing Hematopoietic Cell Transplant: A Model-Based Dosing Algorithm for Personalized...
- A trial of plerixafor adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe Combined immunodeficiency.
- A trial of alemtuzumab adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe Combined immunodeficiency.
- Combined umbilical cord blood and bone marrow from HLA-identical sibling donors for hematopoietic stem cell transplantation in children with hemoglobinopathies.
- Establishing diagnostic criteria for severe Combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: The Primary Immune Deficiency Treatment Consortiu...
- Effect of Weight and Maturation on Busulfan Clearance in Infants and Small Children Undergoing Hematopoietic Cell Transplantation.
- Newborn screening for severe Combined immunodeficiency and T-cell lymphopenia in California: Results of the first 2 years.
- The natural history of children with severe Combined immunodeficiency: baseline features of the first fifty patients of the primary immune deficiency treatment consort...
- Unresolved issues in hematopoietic stem cell transplantation for severe Combined immunodeficiency: Need for safer conditioning and reduced late effects.
- Haploidentical related-donor hematopoietic cell transplantation in children using megadoses of CliniMACs-selected CD34(+) cells and a fixed CD3(+) dose.
- Hematopoietic cell transplant and use of massage for improved symptom management: results from a pilot randomized control trial.
- IL-21 is the primary common gamma chain-binding cytokine required for human B-cell differentiation in vivo.
- T Cell and B Cell Immunity can be Reconstituted with Mismatched Hematopoietic Stem Cell Transplantation Without Alkylator Therapy in Artemis-Deficient Mice Using Anti-...
- Genotype, phenotype, and outcomes of nine patients with T-B+NK+ SCID.
- Hematopoietic stem cell transplantation for CD3? Deficiency.
- Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo.
- Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic cell transplantation between 1980-2009: an internati...
- HLA-matched sibling bone marrow transplantation for β-thalassemia major.
- Chronic granulomatous disease: lessons from a rare disorder.
- Advancement of pediatric blood and marrow transplantation research in North America: priorities of the Pediatric Blood and Marrow Transplant Consortium.
- Reduced-intensity conditioning regimens for allogeneic transplantation in children with acute lymphoblastic leukemia.
- Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunoDeficiency.
- Cytotoxicity associated with artemis overexpression after lentiviral vector-mediated gene transfer.
- Radiosensitive severe Combined immunodeficiency disease.
- Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
- Allogeneic hematopoietic cell transplantation for refractory myasthenia gravis.
- Primary graft failure after umbilical cord blood transplant rescued by parental haplocompatible stem cell transplantation.
- The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation.
- A non-leaky Artemis-deficient mouse that accurately models the human severe Combined immune deficiency phenotype, including resistance to hematopoietic stem cell trans...
- Airway management in children with mucopolysaccharidoses.
- Wiskott-Aldrich syndrome: diagnosis, clinical and laboratory manifestations, and treatment.
- Allogeneic hematopoietic cell transplantation for primary immune Deficiency diseases: current status and critical needs.
- Megadose CD34(+) cell grafts improve recovery of T cell engraftment but not B cell immunity in patients with severe Combined immunodeficiency disease undergoing haploc...
- Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe Combined immunodeficiency.
- Hematopoietic stem cell transplantation for severe Combined immunodeficiency diseases.
- Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease.
- B7.2-/- mature dendritic cells generate T-helper 2 and regulatory T donor cells in fetal mice after in utero allogeneic bone marrow transplantation.
- Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation.
- Simian immunoDeficiency virus infection of hematopoietic stem cells and bone marrow stromal cells.
- Multilineage engraftment with minimal graft-versus-host disease following in utero transplantation of S-59 psoralen/ultraviolet a light-treated, sensitized T cells and...
- A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans.
- Immunization of hematopoietic stem cell transplant recipients against vaccine-preventable diseases.
- A novel missense RAG-1 mutation results in T-B-NK+ SCID in Athabascan-speaking Dine Indians from the Canadian Northwest Territories.
- Improving cellular therapy for primary immune Deficiency diseases: recognition, diagnosis, and management.
- Artemis Deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression.
- Prenatal diagnosis and carrier detection for Athabascan severe Combined immunodeficiency disease.
- Infusion of cytomegalovirus specific cytotoxic T lymphocytes from a sero-negative donor can facilitate resolution of infection and immune reconstitution.
- Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors, and outcome in a cohort of 241 patients.
- X-linked lymphoproliferative disease due to SAP/SH2D1A Deficiency: a multicenter study on the manifestations, management and outcome of the disease.
- Malignancies after hematopoietic cell transplantation for primary immune deficiencies: a report from the Center for International Blood and Marrow Transplant Research.
- Two-tiered universal newborn screening strategy for severe Combined immunodeficiency.
- The missing vital sign.
- A novel human autoimmune syndrome caused by Combined hypomorphic and activating mutations in ZAP-70.
- Evaluation of Pre-Hematopoietic Cell Transplantation (HCT) Brain MRI and Neurologic Complications of Pediatric Patients Undergoing HCT for Hematologic Malignancies.
Schools
Perelman School of Medicine University of Pennsylvania
Conditions Treated
- Combined Immunity Deficiency
- Rash
Doctors Specialties
- Pediatrics
- Allergy
- Immunology
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- Super Doctor
Education
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UCSF -
Duke University Hospital -
Perelman School of Medicine at the University of Pennsylvania
Hospital
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UCSF Medical Center
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