Professor, Internal Medicine, University of Michigan Medical School
Internal Medicine
Dr. Matthias Kretzler, MD
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Matthias Kretzler practices Internal Medicine. He over the years received 2 awards: "CMS Meaningful Use Stage 1 Certification" and "Elected Member". Doctor Matthias Kretzler, MD is also a published MD. He has 100 publication published. The most recent publication is: mRNA differential display analysis of nephrotic kidney glomeruli. He accepts all Medicare patients.
Publications
- Using Population Genetics to Interrogate the Monogenic Nephrotic Syndrome Diagnosis in a Case Cohort.
- A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular Disease.
- A Transcriptional Map of the Renal Tubule: Linking Structure to Function.
- A cis-eQTL in PFKFB2 is associated With diabetic nephropathy, adiposity and insulin secretion in American Indians.
- Lupus Nephritis Susceptibility Loci in Women With Systemic Lupus Erythematosus.
- Integrative Biology Identifies Shared Transcriptional Networks in CKD.
- Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease.
- Defining Nephrotic syndrome from an integrative genomics perspective.
- Identification of stage specific genes associated With lupus nephritis and response to remission induction in NZB/W and NZM2410 mice.
- Systematically Differentiating Functions for Alternatively Spliced Isoforms through Integrating RNA-seq Data.
- Cyclodextrin protects podocytes in diabetic Kidney disease.
- Fn14 in podocytes and proteinuric Kidney disease.
- Defining cell-type specificity at the transcriptional level in human Disease.
- The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in Systemic lupus erythematosus.
- Diabetic Nephropathy: A National Dialogue.
- Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.
- Transcriptome Analysis of Proximal Tubular Cells (HK-2) Exposed to Urines of Type 1 Diabetes Patients at Risk of Early Progressive Renal Function Decline.
- From SNP to Transcriptional Mechanism: A Model for FRMD3 in Diabetic Nephropathy.
- Digital Pathology Evaluation in the Multicenter Nephrotic Syndrome Study Network (NEPTUNE).
- Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular Nephropathy by a multidisciplinary approach.
- Identification of cross-species shared transcriptional networks of diabetic Nephropathy in human and mouse glomeruli.
- Perspectives on systems biology applications in diabetic Kidney disease.
- Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus Nephritis.
- Formal concept analysis of Disease similarity.
- Fibroblast growth factor 23 and Inflammation in CKD.
- Genomic biomarkers for chronic Kidney disease.
- From the Large Scale Expression Analysis of Lupus Nephritis to Targeted Molecular Medicine.
- Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in Diabetes mellitus.
- Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated Nephropathy.
- The identification of gene expression profiles associated With progression of human diabetic neuropathy.
- A systems view of genetics in chronic Kidney disease.
- Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in Systemic lupus erythematosus.
- Urine glycoprotein profile reveals novel markers for chronic Kidney disease.
- Bcl-2-Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice.
- [Gene expression analyses of Kidney biopsies: the European renal cDNA bank--Kröner-Fresenius biopsy bank].
- [Transcriptomics illustrate a deadly TRAIL to diabetic Nephropathy].
- Expression of the chemokine receptor CXCR1 in human glomerular Diseases.
- [Gene expression profiling in prostatic cancer].
- The glomerular mesangium: capillary support function and its Failure under experimental conditions.
- Podocyte damage is a critical step in the development of glomerulosclerosis in the uninephrectomised-desoxycorticosterone Hypertensive rat.
- Renin and renin mRNA in proximal tubules of the rat Kidney.
- The role of podocytes in the development of glomerular sclerosis.
- Stability and leakiness: opposing challenges to the glomerulus.
- Novel mouse embryonic renal marker gene products differentially expressed during Kidney development.
- Regulation of endothelin production and secretion in cultured collecting duct cells by endogenous transforming growth factor-beta.
- A frequent pathway to glomerulosclerosis: deterioration of tuft architecture-podocyte damage-segmental sclerosis.
- Analysis of mouse glomerular podocyte mRNA by single-cell reverse transcription-polymerase chain reaction.
- Expression of glucose transporters in human peritoneal mesothelial cells.
- Single cell RT-PCR analysis of ClC-2 mRNA expression in ureteric bud tip.
- Detection of multiple vascular endothelial growth factor splice isoforms in single glomerular podocytes.
- mRNA differential display analysis of nephrotic Kidney glomeruli.
- Comparative Transcriptional Profiling of 3 Murine Models of SLE Nephritis Reveals Both Unique and Shared Regulatory Networks.
- Altered gene expression and functions of mitochondria in human Nephrotic syndrome.
- Re-expression of the developmental gene Pax-2 during experimental Acute tubular necrosis in mice 1.
- The glomerular slit diaphragm is a modified adherens junction.
- Molecular cloning, expression, and distribution of glomerular epithelial protein 1 in developing mouse Kidney.
- Expression of chemokines and their receptors in nephrotoxic serum Nephritis.
- The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins.
- Chemokine and chemokine receptor expression during initiation and resolution of immune complex Glomerulonephritis.
- Altering glomerular epithelial function in vitro using transient and stable transfection.
- Integrin-linked kinase as a candidate downstream effector in Proteinuria.
- Gene-level integrated metric of negative selection (GIMS) prioritizes candidate genes for Nephrotic syndrome.
- Interaction of DAP3 and FADD only after cellular disruption.
- Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue.
- Quantitative gene expression analysis in Renal biopsies: a novel protocol for a high-throughput multicenter application.
- A chemokine receptor CCR-1 antagonist reduces Renal fibrosis after unilateral ureter ligation.
- Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells.
- Spatial and temporally restricted expression of chemokines and chemokine receptors in the developing human Kidney.
- Roles of SLC/CCL21 and CCR7 in human Kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis.
- Regulation of adhesive interaction between podocytes and glomerular basement membrane.
- Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue.
- Repuncturing the Renal biopsy: strategies for molecular diagnosis in nephrology.
- Characterization of a Na(+)-Ca(2+) exchanger in podocytes.
- TRAIL-induced apoptosis is independent of the mitochondrial apoptosis mediator DAP3.
- Gene expression analysis in microdissected Renal tissue. Current challenges and strategies.
- Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury.
- Cell biology of the glomerular podocyte.
- Bacterial CpG-DNA aggravates immune complex Glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors.
- Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes.
- PDGF-C expression in the developing and normal adult human Kidney and in glomerular diseases.
- Validation of endogenous controls for gene expression analysis in microdissected human Renal biopsies.
- Modification of the transcriptomic response to Renal ischemia/reperfusion injury by lipoxin analog.
- Gene-expression analysis of microdissected Renal biopsies.
- Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a.
- Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric Diseases.
- Post-translational and cell type-specific regulation of CXCR4 expression by cytokines.
- Early glomerular filtration defect and severe renal Disease in podocin-deficient mice.
- Strategy and rationale for urine collection protocols employed in the NEPTUNE study.
- Activation of toll-like receptor-9 induces progression of renal Disease in MRL-Fas(lpr) mice.
- CXCR3 is involved in tubulointerstitial injury in human Glomerulonephritis.
- Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent Renal fibrosis after unilateral ureteral obstruction.
- Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of Disease progression.
- Gene expression analysis in Renal biopsies.
- Gene expression analysis of human renal biopsies: recent developments towards molecular diagnosis of Kidney disease.
- Induction of B7-1 in podocytes is associated With nephrotic syndrome.
- New immunosuppressive strategies in Renal transplant recipients.
- Late onset of treatment With a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice.
- Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium.
- Transcriptional networks of murine diabetic peripheral neuropathy and Nephropathy: common and distinct gene expression patterns.
Schools
RuprechtKarlsUniversitaet Heidelberg Medizinische Gesamtfakultat
Conditions Treated
- Acute Kidney Failure
- Alkalosis
- Calcium Metabolism Disorders
- Chronic GlomeruloNephritis
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Doctors Specialties
- Nephrology
- Internal Medicine
Accepted Insurances
- Choice Plus POS II
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Blue Care Network PCP Focus Network
- Group Employees PPO
- Cigna HMO
- Cigna PPO
- Open Access Plus
- Cofinity PPO
- Commercial Insurance Company
- First Health (Coventry Health Care) PPO
- Golden Rule
- Health Alliance
- Preferred PPO
- Choice Care PPO
- Medicaid
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- PHP-Physicians Health Plan
- Choice Plus POS
- Options PPO
- United Healthcare
Awards
- CMS Meaningful Use Stage 1 Certification
- Elected Member
Education
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University of Heidelberg Faculty of Clinical Medicine
Hospital
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University of Michigan Hospitals and Health Centers
Drug Facts
| NPI NUMBER | 1710990916 | |
| NPPES Provider LastName | KRETZLER | |
| NPPES Provider FirstName | MATTHIAS | |
| NPPES Provider ZIPCode | 481095364 | |
| NPPES Provider State | MI | |
| Specialty Description | Nephrology | |
| Total Claim Count | 265.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1710990916 |
| Last Name Of The Provider | KRETZLER |
| First Name Of The Provider | MATTHIAS |
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