Physician
Cardiology
Dr. Marc S. Penn, MD
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Marc Penn practices Cardiology. He studied medicine at Case Western Reserve University School of Medicine. He received awards:"CMS Meaningful Use Stage 1 Certification" and "Fellow (FACC)". Marc Penn has written publications. He has 101 publications published with PubMed. The lastest publication is: 'Effects of exercise on c-reactive protein in healthy patients and in patients with heart disease: A meta-analysis.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Effects of exercise on c-reactive protein in healthy patients and in patients with heart Disease: A meta-analysis.
- Early up-regulation of myocardial CXCR4 expression is critical for Dimethyloxalylglycine (DMOG) induced cardiac improvement in Acute myocardial infarction (MI).
- Mesenchymal stem cells and their secretome partially restore nerve and urethral function in a dual muscle and nerve injury stress urinary incontinence model.
- Improved conduction and increased cell retention in healed MI using mesenchymal stem cells suspended in alginate hydrogel.
- The role of CXCL12 and CCL7 chemokines in immune regulation, embryonic development, and tissue regeneration.
- Apolipoprotein A1 regulates coenzyme q10 absorption, mitochondrial function, and infarct size in a mouse model of Myocardial infarction.
- Preliminary Observations on MRI Correlates of Driving Independence and Performance in Persons with Heart Failure.
- Functional Outcome After Anal Sphincter Injury and Treatment With Mesenchymal Stem Cells.
- Stem cell therapy for heart Disease.
- The importance of understanding the molecular mechanism of stem cell-induced cardiac tissue repair.
- Multimarker approach for identifying and documenting mitigation of cardiovascular risk.
- Impact of parturition on chemokine homing factor expression in the vaginal distention model of stress urinary incontinence.
- An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic Heart fail...
- Regenerative strategies for preserving and restoring cardiac function.
- Mesenchymal stem cells can improve anal pressures after anal sphincter injury.
- Novel mechanisms for maintaining endothelial barrier function in sepsis.
- Are stem cells the teacher or the student?
- Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following Acute myocardial infarction.
- How similar are the mice to men? Between-species comparison of left ventricular mechanics using strain imaging.
- Stem cell effects at a distance.
- Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload.
- SDF-1 in Myocardial repair.
- Detection and quantification of fluorescent cell clusters in cryo-imaging.
- Coronary collateral growth-Back to the future.
- A tale of 2 biologies: stem cell patch: Myocardial interactions are critical for Myocardial regeneration.
- Adventitial Delivery of an Allogeneic Bone Marrow-Derived Adherent Stem Cell in Acute Myocardial Infarction: Phase I Clinical Study.
- Optical mapping of cryoinjured rat myocardium grafted with mesenchymal stem cells.
- Percutaneous Adventitial Delivery of Allogeneic Bone Marrow Derived Stem Cells Via Infarct Related Artery Improves Long-term Ventricular Function in Acute Myocardial I...
- miR-145 is differentially regulated by TGF?1 and ischemia and targets disabled-2 expression and wnt/?-catenin activity.
- Stromal cell-derived factor-1 and monocyte chemotactic protein-3 improve recruitment of osteogenic cells into sites of musculoskeletal repair.
- Youth is wasted on the young.
- Central role for disabled-2 in mesenchymal stem cardiac protein expression and functional consequences after engraftment in Acute myocardial infarction.
- Combining censored and uncensored data in a u-statistic: design and sample size implications for cell therapy research.
- Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated Cardiomyopathy.
- SDF-1:CXCR4 axis is fundamental for tissue preservation and repair.
- Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after Acute myocardial infarction.
- Heart-brain medicine: update 2009.
- Searching for understanding with the cellular lining of life.
- Critical role for leukocyte hypoxia inducible factor-1alpha expression in post-Myocardial infarction left ventricular remodeling.
- Bone marrow support of the Heart in pressure overload is lost with aging.
- From mice to men. Commonalities in physiology for stem cell-based cardiac repair.
- Speckle tracking echocardiography in the assessment of mouse models of cardiac dysfunction.
- Importance of the SDF-1:CXCR4 axis in Myocardial repair.
- Heart-brain medicine: Update 2008.
- Quantitative intracellular magnetic nanoparticle uptake measured by live cell magnetophoresis.
- Permeability change of arterial endothelium is an age-dependent function of lesion size in apolipoprotein E-null mice.
- Genetic enhancement of stem cell engraftment, survival, and efficacy.
- The role of leukocyte-generated oxidants in left ventricular remodeling.
- Heart-brain medicine: update 2007.
- Preconditioning paradigms and pathways in the brain.
- SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after Myocardial infarction.
- Beta 1-adrenergic receptor autoantibodies mediate dilated Cardiomyopathy by agonistically inducing cardiomyocyte apoptosis.
- Effect of cell-based intercellular delivery of transcription factor GATA4 on ischemic Cardiomyopathy.
- Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of Myocardial infarction.
- Patient and cellular characteristics determine efficacy of cell therapy.
- Over expression of stem cell homing cytokines in urogenital organs following vaginal distention.
- Heart-brain medicine: where we go from here and why.
- Monocyte chemotactic protein-3 is a Myocardial mesenchymal stem cell homing factor.
- SDF-1 recruits cardiac stem cell-like cells that depolarize in vivo.
- Granulocyte colony stimulating factor in patients with large Acute myocardial infarction: results of a pilot dose-escalation randomized trial.
- Mechanical and electrical effects of cell-based gene therapy for ischemic Cardiomyopathy are independent.
- Scaling of diastolic intraventricular pressure gradients is related to filling time duration.
- An elderly man with syncope caused by right ventricular infarction and anomalous Coronary vasculature.
- Peroxisome proliferator-activated receptor gamma down-regulates receptor for advanced glycation end products and inhibits smooth muscle cell proliferation in a diabeti...
- Optical mapping of late Myocardial infarction in rats.
- Stem cells in cardiovascular Disease: methods and protocols.
- Engineered cell therapy for sustained local Myocardial delivery of nonsecreted proteins.
- Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after Myocardial infarction.
- Macromolecular transport in the arterial wall: alternative models for estimating barriers.
- Alterations in internal elastic lamina permeability as a function of age and anatomical site precede lesion development in apolipoprotein E-null mice.
- Platelet, not endothelial, P-selectin is required for neointimal formation after vascular injury.
- Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic bal...
- Latency and substrate binding globally reduce solvent accessibility of plasminogen activator inhibitor type 1 (PAI-1). An adaptation of PAI-1 conformer crystal structu...
- Serum myeloperoxidase levels independently predict endothelial dysfunction in humans.
- Cellular, but not direct, adenoviral delivery of vascular endothelial growth factor results in improved left ventricular function and neovascularization in dilated isc...
- Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species.
- Prognostic value of myeloperoxidase in patients with chest pain.
- Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration.
- Statins promote potent systemic antioxidant effects through specific inflammatory pathways.
- Increased expression of thrombospondin-1 in vessel wall of diabetic Zucker rat.
- Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury.
- Local adenoviral-mediated inducible nitric oxide synthase gene transfer inhibits neointimal formation in the porcine Coronary stented model.
- Association of nitrotyrosine levels with cardiovascular Disease and modulation by statin therapy.
- Angioplasty, inflammation, and antiplatelet agents.
- Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after Myocardial infarction.
- Lysophosphatidic acid induction of tissue factor expression in Aortic smooth muscle cells.
- Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains Coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model.
- Bacterial Endocarditis and functional mitral stenosis: a report of two cases and brief literature review.
- Administration of recombinant P-selectin glycoprotein ligand Fc fusion protein suppresses inflammation and neointimal formation in Zucker diabetic rat model.
- Increased tissue factor expression predicts development of cardiac allograft vasculopathy.
- Autologous cell transplantation for the treatment of damaged myocardium.
- Targeted gene therapy for the treatment of cardiac dysfunction.
- Bone Marrow SSEA1+ Cells Support the Myocardium in Cardiac Pressure Overload.
- Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following Acute myocardial infarction on left ventricular function: the LateT...
- Cardiogenic shock in the setting of severe Aortic stenosis: role of intra-Aortic balloon pump support.
- Critical role for white blood cell NAD(P)H oxidase-mediated plasminogen activator inhibitor-1 oxidation and ventricular rupture following Acute myocardial infarction.
- LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2...
- Intramyocardial injection of autologous bone marrow mononuclear cells for patients with chronic ischemic heart Disease and left ventricular dysfunction (First Mononucl...
- Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained Coronary artery recanalisation with recovery of myocardium perfusion in a can...
- Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bon...
Schools
Case Western Reserve University School of Medicine
Cleveland Clinic Foundation
Procedures Preformed
- Ablation for Treatment of Cardiac Arrhythmias
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardioversion, Elective
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Conditions Treated
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow (FACC)
Education
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Cleveland Clinic Foundation -
Case Western Reserve University - University Hospitals -
Case Western Reserve University School of Medicine
Hospital
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Cleveland Clinic -
Summa Akron City Hospital
Drug Facts
| NPI NUMBER | 1679665228 | |
| NPPES Provider LastName | PENN | |
| NPPES Provider FirstName | MARC | |
| NPPES Provider ZIPCode | 44304 | |
| NPPES Provider State | OH | |
| Specialty Description | Cardiology | |
| Total Claim Count | 48.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1679665228 |
| Last Name Of The Provider | PENN |
| First Name Of The Provider | MARC |
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