Assistant Adjunct Professor of Pediatrics
Neonat/Perinatology
Dr. Luke M. Judge, MD
Luke Judge practices Neonat/Perinatology. He researched medicine at University of Washington School of Medicine. Doctor Luke M. Judge, MD is also a published doctor. He has 12 publication published. The most recent publication is: CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Publications
- Automated video-based analysis of contractility and calcium flux in human iPS-derived cardiomyocytes cultured over different spatial scales.
- Isolation of single-base genome-edited human iPS cells without antibiotic selection.
- Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.
- The polyproline site in hinge 2 influences the functional capacity of truncated dystrophins.
- Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.
- Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.
- Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.
- Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
- Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex.
- Gene therapy for Duchenne muscular dystrophy: AAV leads the way.
- CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Schools
University of Washington
Doctors Specialties
- Pediatrics
- Neonat/Perinatology
Accepted Insurances
Education
-
UCSF -
University of Washington School of Medicine
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