Executive Director, HIV Vaccine Trials Network; Medical Director, Malaria Clinical Trials Center
Preventive Medicine
Dr. James G. Kublin, MD
Dr. James G. Kublin is an expert in the field of Preventive Medicine. He attended Georgetown University School of Medicine. Georgetown University School of Medicine has a rank of 49 in research and a 84 in primary care James Kublin has written publications. He has 31 publications published with PubMed. The lastest paper is: 'Are Clade Specific HIV Vaccines a Necessity? An Analysis Based on Mathematical Models.'
Publications
- Selection of HIV vaccine candidates for concurrent testing in an efficacy trial.
- Are Clade Specific HIV Vaccines a Necessity? An Analysis Based on Mathematical Models.
- Multiple factors affect immunogenicity of DNA plasmid HIV vaccines in human clinical trials.
- Persistence of Sulfadoxine-Pyrimethamine Resistance Despite Reduction of Drug Pressure in Malawi.
- A New Model for Catalyzing Translational Science: The Early Stage Investigator Mentored Research Scholar Program in HIV Vaccines.
- Tuberculosis Vaccines and Prevention of Infection.
- Use of placebos in Phase 1 preventive HIV vaccine clinical trials.
- Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study.
- Understanding HIV epidemics: aggregate viral load metrics and 'smoking guns'.
- Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine.
- The HVTN503/Phambili HIV vaccine trial: A comparison of younger and older participants.
- Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery.
- Lessons Learned from HIV Vaccine Clinical Efficacy Trials.
- Have the explosive HIV epidemics in sub-Saharan Africa been driven by higher community viral load?
- In Pursuit of an HIV Vaccine: Designing Efficacy Trials in the Context of Partially Effective Non-Vaccine Prevention Modalities.
- Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine.
- A Sequential Phase 2b Trial Design for Evaluating Vaccine Efficacy and Immune Correlates for Multiple HIV Vaccine Regimens.
- Pre-Existing Adenovirus Immunity Modifies a Complex Mixed Th1 and Th2 Cytokine Response to an Ad5/HIV-1 Vaccine Candidate in Humans.
- Comparative cell-mediated immunogenicity of DNA/DNA, DNA/adenovirus type 5 (Ad5), or Ad5/Ad5 HIV-1 clade B gag vaccine prime-boost regimens.
- Challenges in the prevention, diagnosis, and treatment of malaria in human immunodeficiency virus infected adults in sub-Saharan Africa.
- Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa.
- Parasitic central nervous system infections in immunocompromised hosts: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis.
- HIV infection and malaria--understanding the interactions.
- Effects of HIV-1 serostatus, HIV-1 RNA concentration, and CD4 cell count on the incidence of malaria infection in a cohort of adults in rural Malawi.
- Association between the pharmacokinetics and in vivo therapeutic efficacy of sulfadoxine-pyrimethamine in Malawian children.
- Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria.
- Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites.
- Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi.
- Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria.
- Safety and Comparability of Controlled Human Plasmodium falciparum Infection by Mosquito Bite in Malaria-Naïve Subjects at a New Facility for Sporozoite Challenge.
Schools
Georgetown University
Doctors Specialties
- Preventive Public Health Medicine
- Preventive Medicine
Accepted Insurances
Education
-
Johns Hopkins Bloomberg School of Public Health -
Georgetown University School of Medicine
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