Associate Professor, Pediatrics, University of Texas Southwestern Medical Center, Southwestern Medical School

Oncology

Doctor James F. Amatruda, MD is an expert in the field of Oncology. He went to medical school at Washington University School of Medicine in St. Louis. James Amatruda is also published. He has 32 publications published. The lastest publication: "Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.'

Publications

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• Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative.
• The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response.
• Parents' Preferences for Return of Results in Pediatric Genomic Research.
• Autophagy is essential for cardiac morphogenesis during vertebrate development.
• A big catch for germ Cell tumour research.
• The Development of Highly Potent Inhibitors for Porcupine.
• C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury.
• Multiple isoforms of CDC25 oppose ATM activity to maintain Cell proliferation during vertebrate development.
• Studying synthetic lethal interactions in the zebrafish system: insight into Disease genes and mechanisms.
• A zebrafish transgenic model of Ewing''s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
• Mutation in the type IB bone morphogenetic protein receptor alk6b impairs germ-Cell differentiation and causes germ-Cell tumors in zebrafish.
• High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.
• Zebrafish models of germ Cell tumor.
• Genome-wide RNAi screen reveals Disease-associated genes that are common to Hedgehog and Wnt signaling.
• Analysis of Cell proliferation, senescence, and Cell death in zebrafish embryos.
• Breast cancer between faith and medicine: the Peres Maldonado ex-voto.
• Trends in incidence and survival of pediatric and adolescent patients with germ Cell tumors in the United States, 1975 to 2006.
• Effect of vascular cadherin knockdown on zebrafish vasculature during development.
• Identification of a heritable model of testicular germ Cell tumor in the zebrafish.
• Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.
• Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.
• Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.
• A mutation in separase causes genome instability and increased susceptibility to epithelial cancer.
• The INT6 cancer gene and MEK signaling pathways converge during zebrafish development.
• Small molecules that delay S phase suppress a zebrafish bmyb mutant.
• A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
• Analysis of the Cell cycle in zebrafish embryos.
• Zebrafish as a cancer model system.
• Recurrent internal tandem duplications of BCOR in clear Cell sarcoma of the kidney.
• DNA methylation analysis reveals distinct methylation signatures in pediatric germ Cell tumors.
• Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.

Conditions Treated

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• Anemia
• Sickle Cell Disease

Doctors Specialties

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• Medical Oncology
• Oncology
• Pediatric Infectious Disease Medicine

Accepted Insurances

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• Aetna HMO
• Choice Plus POS II
• Blue Card PPO
• Blue Choice
• Cigna HMO
• Cigna PPO
• Great West Healthcare-Cigna PPO
• LocalPlus
• Open Access Plus
• First Health (Coventry Health Care) PPO
• Choice Care PPO
• Preferred PPO
• PHCS Network PPO
• Choice Plus POS
• Navigate HMO
• Navigate POS
• Options PPO

Education

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• Brigham and Women's Hospital
• Washington University School of Medicine in St. Louis

Hospital

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• University of Texas Southwestern Medical Center
• Children's Health System of Texas

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