Associate Professor
Radiology
Dr. Gary D. Luker, MD
|
|
Give Review
Gary Luker works in the field of Radiology. He went to Washington University School of Medicine in St. Louis. He has 1 awards "Elected Member". Gary D. Luker is also published. He has 101 publications published. The lastest publication: "Skeletal surveys for child abuse: comparison of interpretation using digitized images and screen-film radiographs.'
Publications
- CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.
- Microscale 3D Collagen Cell Culture Assays in Conventional Flat-Bottom 384-Well Plates.
- Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model.
- Surface-templated hydrogel patterns prompt matrix-dependent migration of breast cancer cells towards chemokine-secreting cells.
- High Throughput, Polymeric Aqueous Two-Phase Printing of Tumor Spheroids.
- Optimization of Aqueous Biphasic Tumor Spheroid Microtechnology for Anti-Cancer Drug Testing in 3D Culture.
- CXCL12-γ in primary tumors drives breast cancer metastasis.
- A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer(1,2.)
- Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis.
- Simple Multi-level Microchannel Fabrication by Pseudo-Grayscale Backside Diffused Light Lithography.
- Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7.
- Transfer, Imaging, and Analysis Plate for Facile Handling of 384 Hanging Drop 3D Tissue Spheroids.
- Host derived CD8+ dendritic cells are required for induction of optimal graft-versus-tumor responses after experimental allogeneic bone marrow transplantation.
- Imaging CXCL12-CXCR4 Signaling in Ovarian Cancer Therapy.
- Advancing the translation of optical imaging agents for clinical imaging.
- Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.
- Rapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning.
- Cell-based and in vivo spectral analysis of fluorescent proteins for multiphoton microscopy.
- Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.
- Secreted CXCL12 (SDF-1) Forms Dimers under Physiologic Conditions.
- In vivo imaging of ligand receptor binding with Gaussia luciferase complementation.
- Targeted non-covalent self-assembled nanoparticles based on human serum albumin.
- CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity.
- Luciferase protein complementation assays for bioluminescence imaging of cells and mice.
- Synthesis and Investigation of a Radioiodinated F3 Peptide Analog as a SPECT Tumor Imaging Radioligand.
- Longitudinal Molecular Imaging with Single Cell Resolution of Disseminated Ovarian Cancer in Mice with a LED-based Confocal Microendoscope.
- Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow.
- Near-infrared fluorescent proteins.
- Imaging chemokine receptor dimerization with firefly luciferase complementation.
- Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells.
- Real-time bioluminescence imaging of viral pathogenesis.
- Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging.
- Imaging CXCR4 signaling with firefly luciferase complementation.
- Monitoring serial changes in circulating human breast cancer cells in murine xenograft models.
- Extended cavity laser enhanced two-photon flow cytometry.
- In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry.
- A novel, killed-virus nasal vaccinia virus vaccine.
- Optical imaging: current applications and future directions.
- Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection.
- TLR3 increases disease morbidity and mortality from vaccinia infection.
- Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production.
- CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature.
- Murine alveolar macrophages limit replication of vaccinia virus.
- Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II.
- Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice.
- Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread.
- Luciferase real-time bioluminescence imaging for the study of viral pathogenesis.
- CXCR4 regulates growth of both primary and metastatic breast cancer.
- Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals.
- Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.
- Bioluminescence imaging reveals systemic dissemination of herpes simplex virus type 1 in the absence of interferon receptors.
- Imaging 26S proteasome activity and inhibition in living mice.
- Imaging pulmonary gene expression with positron emission tomography.
- Molecular imaging of protein-protein interactions: controlled expression of p53 and large T-antigen fusion proteins in vivo.
- Visualizing protein-protein interactions in living animals.
- Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice.
- Molecular imaging of gene expression and protein function in vivo with PET and SPECT.
- Noninvasive imaging of protein-protein interactions in living animals.
- In vitro and in vivo characterization of a dual-function green fluorescent protein--HSV1-thymidine kinase reporter gene driven by the human elongation factor 1 alpha p...
- Special conference of the American Association for Cancer Research on molecular imaging in cancer: linking biology, function, and clinical applications in vivo.
- CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7.
- Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4.
- Applications of molecular imaging.
- Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells.
- Imaging ligand-dependent activation of CXCR7.
- Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids.
- Bioluminescence imaging of reporter mice for studies of infection and inflammation.
- Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation.
- Applications of bioluminescence imaging to the study of infectious diseases.
- Functions of CXCL12 and CXCR4 in breast cancer.
- Nanolitre liquid patterning in aqueous environments for spatially defined reagent delivery to mammalian cells.
- Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands.
- Cerebral infarction in sickle cell disease: transcranial Doppler US versus neurologic examination.
- High costs of low-osmolality contrast media.
- Pediatric applications of helical (spiral) CT.
- Sinus pericranii: sonographic findings.
- Aortic dissection: effect of prospective chest radiographic diagnosis on delay to definitive diagnosis.
- Color Doppler sonography of the scrotum in children.
- Pediatric testicular tumors: evaluation with gray-scale and color Doppler US.
- Mediastinal Hodgkin disease in children: response to therapy.
- Spiral CT of the temporal bone in unsedated pediatric patients.
- Scrotal US in pediatric patients: comparison of power and standard color Doppler US.
- Hepatic spiral CT in children: scan delay time-enhancement analysis.
- Pediatric chest MR imaging. Noncardiac clinical uses.
- MR imaging of the liver in children.
- Ghosting of pulmonary nodules with respiratory motion: comparison of helical and conventional CT using an in vitro pediatric model.
- Modulation of the multidrug resistance P-glycoprotein: detection with technetium-99m-sestamibi in vivo.
- Characterization of phosphine complexes of technetium(III) as transport substrates of the multidrug resistance P-glycoprotein and functional markers of P-glycoprotein ...
- Novel technetium (III)-Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein.
- Skeletal surveys for child abuse: comparison of interpretation using digitized images and screen-film radiographs.
- Soft-copy versus hard-copy interpretation of voiding cystourethrography in neonates, infants, and children.
- Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol.
- Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin.
- Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains.
- Novel Tat-peptide chelates for direct transduction of technetium-99m and rhenium into human cells for imaging and radiotherapy.
- Molecular imaging in vivo with PET and SPECT.
- Decreased hepatic accumulation and enhanced esterification of cholesterol in mice deficient in mdr1a and mdr1b P-glycoproteins.
- MDR1 P-glycoprotein reduces influx of substrates without affecting membrane potential.
- Comparison of shell vial culture and the suspension-infection method for the rapid detection of herpes simplex viruses.
- Termination of antigen-specific immunity by CD95 ligand (Fas ligand) and IL-10.
Schools
Washington Center School of Medicine
Doctors Specialties
- Pediatric Radiology
- Radiology
Accepted Insurances
Awards
- Elected Member
Education
-
Washington University - Barnes-Jewish Hospital -
Washington University School of Medicine in St. Louis
Hospital
-
University of Michigan Hospitals and Health Centers
Helpful Reviews
Similar Doctors
|
|
Dr. Jason G. Domina, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Caroline E. Blane, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Neil J. Hansen, MD |
|
|
Dr. Kathleen M. Gebarski, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Prachi P. Agarwal, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Maria F. Ladino Torres, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Morand R. Piert, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Narasimham L. Dasika, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Ayman H. Gaballah, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Maria A. Komissarova, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. John Pietila, MD |
|
|
Dr. Matthew D. Hermann, MD |
|
|
Dr. George C. Koberlein, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Hatice Savas, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Jeet Patel |