Professor of Pediatrics, Johns Hopkins University School of Medicine
Neonat/Perinatology
Dr. Frances J. Northington, MD
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Frances Northington practices Neonat/Perinatology. She researched medicine at University of Arkansas for Medical Sciences. University of Arkansas for Medical Sciences is ranked 83/35 in Research/PrimaryCare. Frances J. Northington has written publications. She has 64 publications published with PubMed. The lastest paper is: 'Lack of induction of substance P gene expression by hypoxia and absence of neurokinin 1-receptor mRNAs in the rat carotid body.'
Publications
- Endoplasmic reticulum pathology and stress response in neurons precede programmed necrosis after neonatal hypoxia-ischemia.
- Steady pulsed imaging and labeling scheme for noninvasive perfusion imaging.
- Prenatal Cerebellar Hemorrhage: Fetal and Postnatal Neuroimaging Findings and Postnatal Outcome.
- Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia-ischemia injured mouse brains.
- Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats.
- Neonatal neuroimaging findings in congenital myotonic dystrophy.
- Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography.
- Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1.
- In vivo high-resolution diffusion tensor imaging of the mouse brain.
- Reply to: Is There Really a Need to Adjust Gentamicin Dosing in Neonates Treated With Hypothermia?
- Imaging neurodegeneration in the mouse hippocampus after neonatal hypoxia-ischemia using oscillating gradient diffusion MRI.
- Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy.
- Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia.
- Accuracy of head ultrasound for the detection of intracranial hemorrhage in preterm neonates: Comparison with brain MRI and susceptibility-weighted imaging.
- Neonatal neuroimaging findings in inborn errors of metabolism.
- Susceptibility weighted imaging of the neonatal brain.
- Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury.
- Does Diffusion Tensor Imaging-Based Tractography at 3 Months of Age Contribute to the Prediction of Motor Outcome After Perinatal Arterial Ischemic Stroke?
- Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling.
- Neuronal cell death in neonatal hypoxia-ischemia.
- Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI.
- A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy.
- Delayed neural network degeneration after neonatal hypoxia-ischemia.
- White matter injury correlates with hypertonia in an animal model of cerebral palsy.
- Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice ove...
- Brief update on animal models of hypoxic-ischemic encephalopathy and neonatal stroke.
- Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury.
- Cannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development.
- Increased morbidity in severe early intrauterine growth restriction.
- A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypoth...
- Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - a longitudinal study.
- Treatment advances in neonatal neuroprotection and neurointensive care.
- Ontogeny of retrograde labeled chemoafferent neurons in the newborn rat nodose-petrosal ganglion complex: an ex vivo preparation.
- PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury.
- Apoptosis in perinatal hypoxic-ischemic brain injury: how important is it and should it be inhibited?
- Antioxidant status alters levels of Fas-associated death domain-like IL-1B-converting enzyme inhibitory protein following neonatal hypoxia-ischemia.
- Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice.
- Neonatal brain imaging and the identification of metabolic acidemia and hypoxic-ischemic encephalopathy.
- Large fetal sacrococcygeal teratomas: could early delivery improve outcome?
- X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antio...
- Neurodegeneration in the thalamus following neonatal hypoxia-ischemia is programmed cell death.
- Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis.
- Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis.
- P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate.
- Differential expression of a(2a), A(1)-adenosine and D(2)-dopamine receptor genes in rat peripheral arterial chemoreceptors during postnatal development.
- Delayed presentation of pulmonary interstitial emphysema.
- GLT1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain.
- Brain O2 consumption and glutamate release during hypoglycemic coma in piglets are temperature sensitive.
- Lack of induction of substance P gene expression by hypoxia and absence of neurokinin 1-receptor mRNAs in the rat carotid body.
- Regional and cellular expression of glial (GLT1) and neuronal (EAAC1) glutamate transporter proteins in ovine fetal brain.
- Newborn cerebrovascular responses after first trimester moderate maternal ethanol exposure in sheep.
- Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats.
- Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo.
- Developmental and regional differences in nitric oxide synthase activity and blood flow in the sheep brain.
- Nitric oxide synthase 1 and nitric oxide synthase 3 protein expression is regionally and temporally regulated in fetal brain.
- In vivo production of nitric oxide correlates with NMDA-induced cerebral hyperemia in newborn sheep.
- Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
- Aortic thrombosis after umbilical artery catheterization in neonates: prevalence of complications on long-term follow-up.
- Sciatic nerve stimulation does not increase endogenous adenosine production in sensory-motor cortex.
- Relative responses to luminal and adventitial adenosine in perfused arteries.
- Elevated growth hormone secretory rate in premature infants: deconvolution analysis of pulsatile growth hormone secretion in the neonate.
- Competitive inhibition of nitric oxide synthase prevents the cortical hyperemia associated with peripheral nerve stimulation.
- Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochond...
Schools
Medical College of Georgia
University Of Arkansas For Med Science
Arkansas Children39S Hospital
University Of Virginia Med Center
Doctors Specialties
- Neonatal Medicine
- Neonat/Perinatology
Accepted Insurances
Education
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University of Virginia -
University of Arkansas for Medical Sciences -
Medical College of Georgia School of Medicine
Hospital
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Johns Hopkins Hospital
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