Professor, Dermatology, Pennsylvania State University College of Medicine
Dermatology
Dr. Diane M. Thiboutot, MD
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Diane Thiboutot works in the field of Dermatology. She graduated from Penn State College of Medicine. She over the years received 1 awards: "Fellow (FAAD)". Diane Thiboutot is also a published doctor. She has 101 paper published. The most recent paper is: Oxidative activity of the type 2 isozyme of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) predominates in human sebaceous glands. Doctor Diane M. Thiboutot, MD accepts Medicare payments and is listed with Medicare.gov.
Publications
- Safe Use of Therapeutic-Dose Oral Isotretinoin in Patients With a History of Pseudotumor Cerebri.
- A retrospective analysis of the duration of oral antibiotic therapy for the treatment of Acne among adolescents: Investigating practice gaps and potential cost-savings.
- Inflammasome Activation by Propionibacterium Acnes: The Story of IL-1 in Acne Continues to Unfold.
- Evidence-based recommendations for the diagnosis and treatment of pediatric Acne.
- Isotretinoin and affective disorders: Thirty years later.
- An evaluation of potential correlations between pathophysiologic mechanisms, clinical manifestations, and management of rosacea.
- Acne Vulgaris and the Epidermal Barrier: Is Acne Vulgaris Associated with Inherent Epidermal Abnormalities that Cause Impairment of Barrier Functions? Do Any Topical A...
- The effects of isotretinoin on wisdom tooth extraction.
- Systemic Isotretinoin Therapy Normalizes Exaggerated TLR-2-Mediated Innate Immune Responses in Acne Patients.
- Circulating tumor Cells in melanoma patients.
- Impact of a fixed combination of clindamycin phosphate 1.2%-benzoyl peroxide 2.5% aqueous gel on health-related quality of life in moderate to severe Acne vulgaris.
- A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy.
- Temporal changes in gene expression in the Skin of patients treated with isotretinoin provide insight into its mechanism of action.
- Isotretinoin temporally regulates distinct sets of genes in patient Skin.
- Early gene changes induced by isotretinoin in the Skin provide clues to its mechanism of action.
- Changing the face of Acne therapy.
- Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea.
- Long-term safety and efficacy study of adapalene 0.3% gel.
- Neutrophil gelatinase-associated lipocalin mediates 13-cis retinoic acid-induced apoptosis of human sebaceous gland Cells.
- Overview of Acne and its treatment.
- Improving outcomes through collaboration.
- Pharmacologic modulation of sebaceous gland activity: mechanisms and clinical applications.
- 13-cis Retinoic acid induces apoptosis and Cell cycle arrest in human SEB-1 sebocytes.
- Peroxisome proliferator-activated receptors increase human sebum production.
- Expert committee recommendations for Acne management.
- Treatment considerations for inflammatory Acne: clinical evidence for adapalene 0.1% in combination therapies.
- Insulin-like growth factor-1 induces lipid production in human SEB-1 sebocytes via sterol response element-binding protein-1.
- Gene array expression profiling in Acne lesions reveals marked upregulation of genes involved in inflammation and matrix remodeling.
- Adapalene gel, 0.1%, as maintenance therapy for Acne vulgaris: a randomized, controlled, investigator-blind follow-up of a recent combination study.
- Comparison of tazarotene and minocycline maintenance therapies in Acne vulgaris: a multicenter, double-blind, randomized, parallel-group study.
- Diagnosing and managing the patient with rosacea.
- GI polyposis and glycogenic Acanthosis of the esophagus associated with PTEN mutation positive Cowden syndrome in the absence of cutaneous manifestations.
- Pathogenesis of Acne: recent research advances.
- Diet and Acne revisited.
- Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole Skin.
- Evaluating health-related quality of life in patients with facial Acne: development of a self-administered questionnaire for clinical trials.
- Hormones and Acne: pathophysiology, clinical evaluation, and therapies.
- Acne. Introduction.
- A randomized, controlled trial of a low-dose contraceptive containing 20 microg of ethinyl estradiol and 100 microg of levonorgestrel for Acne treatment.
- Health-related quality of life among patients with facial Acne -- assessment of a new Acne-specific questionnaire.
- The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial Cells.
- Immunolocalization of 5alpha-reductase isozymes in Acne lesions and normal skin.
- New treatments and therapeutic strategies for Acne.
- Androgen metabolism in sebaceous glands from subjects with and without Acne.
- Finasteride in the treatment of men with frontal male pattern Hair loss.
- Oxidative activity of the type 2 isozyme of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) predominates in human sebaceous glands.
- Activity of 5-alpha-reductase and 17-beta-hydroxysteroid dehydrogenase in the infrainfundibulum of subjects with and without Acne vulgaris.
- Immunohistochemical localization of types 1 and 2 5alpha-reductase in human scalp.
- Propecia dosages.
- Randomized controlled trial of the tolerability, safety, and efficacy of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of Acne vulgaris.
- Inhibition of papilloma progression by antisense oligonucleotides targeted to HPV11 E6/E7 RNA.
- Oral isotretinoin and pregnancy prevention programmes.
- The hypothetical role of FoxO1 in Acne is interesting, but more study is needed before any conclusions can be drawn.
- Can sebum reduction predict Acne outcome?
- A clinical overview of azelaic acid.
- Efficacy and tolerability of adapalene 0.3% gel compared to tazarotene 0.1% gel in the treatment of Acne vulgaris.
- Patient experiences with oily Skin: the qualitative development of content for two new patient reported outcome questionnaires.
- Antibiotic use in Acne vulgaris and rosacea: clinical considerations and resistance issues of significance to dermatologists.
- An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe Acne vulgaris: assessment o...
- A combined oral contraceptive containing 3-mg drospirenone/ 20-microg ethinyl estradiol in the treatment of Acne vulgaris: a randomized, double-blind, placebo-controll...
- Hormonal therapy for Acne.
- Histone H4 is a major component of the antimicrobial action of human sebocytes.
- New insights into the management of Acne: an update from the Global Alliance to Improve Outcomes in Acne group.
- Standard management options for rosacea, part 2: options according to subtype.
- Comparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study.
- A 3-step Acne system containing solubilized benzoyl peroxide versus clindamycin-benzoyl peroxide.
- Standard management options for rosacea, part 1: overview and broad spectrum of care.
- Large-scale worldwide observational study of adherence with Acne therapy.
- A Three-Step Acne System Containing Solubilized Benzoyl Peroxide versus Benzoyl Peroxide/Clindamycin in Pediatric Patients with Acne.
- Dermatologists do not yet fully understand the clinical significance of antibiotic use and bacterial resistance in patients with Acne: comment on "Antibiotics, Acne, a...
- Rethinking treatment of Acne in the severe patient.
- Introduction. Challenges in managing Acne patients.
- Pathogenesis of Acne vulgaris: what's new, what's interesting and what may be clinically relevant.
- Efficacy and safety of 3 mg drospirenone/20 mcg ethinylestradiol oral contraceptive administered in 24/4 regimen in the treatment of Acne vulgaris: a randomized, doubl...
- Acne counseling to improve adherence.
- Versatility of azelaic acid 15% gel in treatment of inflammatory Acne vulgaris.
- IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway.
- A double-blinded, randomized, vehicle-controlled, multicenter, parallel-group study to assess the safety and efficacy of tretinoin gel microsphere 0.04% in the treatme...
- Adapalene gel 0.3% for the treatment of Acne vulgaris: a multicenter, randomized, double-blind, controlled, phase III trial.
- Acne: hormonal concepts and therapy.
- Azelaic acid gel 15%: clinical versatility in the treatment of rosacea.
- A systemic type I 5 alpha-reductase inhibitor is ineffective in the treatment of Acne vulgaris.
- Topical retinoids in inflammatory Acne: a retrospective, investigator-blinded, vehicle-controlled, photographic assessment.
- Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and Acne lesion counts in adult women.
- Photographic review of results from a clinical study comparing benzoyl peroxide 5%/clindamycin 1% topical gel with vehicle in the treatment of rosacea.
- Regulation of human sebaceous glands.
- Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies.
- Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte Cell line (SEB-1).
- Update and future of hormonal therapy in Acne.
- Cutaneous androgen metabolism: basic research and clinical perspectives.
- Acne: 1991-2001.
- A randomized, parallel, vehicle-controlled comparison of two erythromycin/benzoyl peroxide preparations for Acne vulgaris.
- Management of Acne: a report from a Global Alliance to Improve Outcomes in Acne.
- Acne and rosacea. New and emerging therapies.
- An overview of Acne and its treatment.
- Interstitial granulomatous Dermatitis with arthritis.
- Occupationally induced allergic contact Dermatitis to methylchloroisothiazolinone/methylisothiazolinone among machinists.
- Acne rosacea.
- Acne: acute or chronic disease?
- Clinical review 74: Dermatological manifestations of endocrine disorders.
Schools
Pennsylvania State University College of Medicine
Penn St University Hp M S Hershey Mc
Procedures Preformed
- Dermal Filler
- Destruction of Benign Skin Lesion
- Destruction of Malignant Skin Lesion
- Excision of Benign Skin Lesion
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Conditions Treated
- Acanthosis Nigricans
- Acne
- Actinic Keratosis
- Athlete's Foot
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Doctors Specialties
- Dermatology
Accepted Insurances
Awards
- Fellow (FAAD)
Education
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Penn State University -
Penn State College of Medicine
Hospital
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Penn State Milton S. Hershey Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1104889831 |
| Last Name Of The Provider | THIBOUTOT |
| First Name Of The Provider | DIANE |
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