Physician
Pathology
Dr. Celina G. Kleer, MD
|
|
Give Review
Doctor Celina G. Kleer, MD works in the field of Pathology. Celina Kleer is also a published doctor. She has 80 publication published. The most recent publication is: Characterizing Breast Cancer in a Population with Increased Prevalence of Triple-Negative Breast Cancer: Androgen Receptor and ALDH1 Expression in Ghanaian Women. Celina G. Kleer, MD accepts Medicare.
Publications
- Characterizing Breast Cancer in a Population with Increased Prevalence of Triple-Negative Breast Cancer: Androgen Receptor and ALDH1 Expression in Ghanaian Women.
- Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer.
- Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors.
- Characterization of type III TGF-β receptor expression in invasive breast carcinomas: a potential new marker and target for triple negative breast cancer.
- Re-Excision Rates of Invasive Ductal Carcinoma with Lobular Features Compared with Invasive Ductal Carcinomas and Invasive Lobular Carcinomas of the Breast.
- EZH2 expands breast stem cells through activation of NOTCH1 signaling.
- SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model.
- EZH2 and ALDH1 expression in ductal carcinoma in situ: Complex association with recurrence and progression to invasive breast cancer.
- Biomarkers in advanced larynx cancer: Triological society thesis.
- Tissue-based identification of stem cells and epithelial-to-mesenchymal transition in breast cancer.
- EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis.
- Invasive ductal carcinoma with lobular features: a comparison study to invasive ductal and invasive lobular carcinomas of the breast.
- HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab.
- CCN6 Knockdown Disrupts Acinar Organization of Breast Cells in Three-dimensional Cultures through Up-regulation of Type III TGF-β Receptor.
- Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression.
- Expression of aldehyde dehydrogenase 1 as a marker of mammary stem cells in benign and malignant breast lesions of Ghanaian women.
- Metaplastic carcinomas of the breast: diagnostic challenges and new translational insights.
- CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer.
- Discoidin domain receptor tyrosine kinases: new players in cancer progression.
- Invasive breast carcinomas in Ghana: high frequency of high grade, basal-like histology and high EZH2 expression.
- Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition.
- p38{gamma} promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior.
- On how CCN6 suppresses breast cancer growth and invasion.
- Survival of Inflammatory Breast Cancer Patients Compared to Non-inflammatory Breast Cancer Patients in Egypt.
- Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression.
- Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer.
- EZH2 and ALDH-1 mark breast epithelium at risk for breast cancer development.
- Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer.
- Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks.
- Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
- African ancestry and higher prevalence of triple-negative breast cancer: findings from an international study.
- Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma.
- Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells.
- Antiangiogenic tetrathiomolybdate protects against Her2/neu-induced breast carcinoma by hypoplastic remodeling of the mammary gland.
- Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions.
- Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia.
- AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
- An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.
- Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy.
- Residual disease after re-excision lumpectomy for close margins.
- Axillary staging prior to neoadjuvant chemotherapy for breast cancer: predictors of recurrence.
- Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression.
- Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.
- Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.
- BRCA1 regulates human mammary stem/progenitor cell fate.
- Sentinel lymph node biopsy for breast cancer: how many nodes are enough?
- ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.
- CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature.
- Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression.
- Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells.
- Significance of flat epithelial atypia on mammotome core needle biopsy: Should it be excised?
- Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor board.
- Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast.
- RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck.
- Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues.
- Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breast.
- Is lobular carcinoma in situ as a component of breast carcinoma a risk factor for local failure after breast-conserving therapy? Results of a matched pair analysis.
- Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis.
- A putative role for psoriasin in breast tumor progression.
- Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy.
- Comprehensive axillary evaluation in neoadjuvant chemotherapy patients with ultrasonography and sentinel lymph node biopsy.
- Alpha-methylacyl-CoA racemase protein expression is associated with the degree of differentiation in breast cancer using quantitative image analysis.
- Pathologic features of breast cancer associated with complete response to neoadjuvant chemotherapy: importance of tumor necrosis.
- A pilot study to establish a clinical model to perform phase II studies of breast cancer chemopreventive agents in women at high risk with biomarkers as surrogate endp...
- Small (< 2.0-cm) breast cancers: mammographic and US findings at US-guided cryoablation--initial experience.
- p63 expression in breast cancer: a highly sensitive and specific marker of metaplastic carcinoma.
- WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancer.
- Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines.
- EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells.
- Sentinel node biopsy prior to neoadjuvant chemotherapy.
- Antiangiogenic tetrathiomolybdate enhances the efficacy of doxorubicin against breast carcinoma.
- Altered receptor trafficking in Huntingtin Interacting Protein 1-transformed cells.
- Lymphocytic mastitis and diabetic mastopathy: a molecular, immunophenotypic, and clinicopathologic evaluation of 11 cases.
- Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.
- Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts.
- Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions.
- Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability.
- Genetic Changes in Chromosomes 1p and 17p in Thyroid Cancer Progression.
- Three Dimensional Cultures: A Tool To Study Normal Acinar Architecture vs. Malignant Transformation Of Breast Cells.
Doctors Specialties
- Pathology
Accepted Insurances
Education
-
University of Michigan Hospitals and Health Centers -
Mayo School of Graduate Medical Education -
University of Buenos Aires
Hospital
-
University of Michigan Hospitals and Health Centers
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1972685923 |
| Last Name Of The Provider | KLEER |
| First Name Of The Provider | CELINA |
| View All |
Similar Doctors
|
|
Dr. Cynthia L. Cookingham, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Stewart M. Knoepp, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Robertson D. Davenport, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Paul E. McKeever, MD
This Doctor is OpenDoctor Recommended.
 This doctor has more publications
|
|
|
Dr. Chisa Yamada, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Lloyd M. Stoolman, MD
This Doctor is OpenDoctor Recommended.
|