Robert W. Kellermeyer Professor, Medicine, Case Western Reserve University School of Medicine
Hematology
Dr. Alvin H. Schmaier, MD
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Alvin H. Schmaier practices Hematology. He attended Virginia Commonwealth University School of Medicine. He over the years received 2 awards: "Regional Top Doctor" and "Elected Member". Dr. Alvin H. Schmaier is a published physician. He has 99 publications published. The most current publication "Mechanism of epinephrine-induced platelet aggregation." He is registered with Medicare and accepts Medicare payments.
Publications
- Plasma Prekallikrein Is Associated With Carotid Intima-Media Thickness in Type 1 Diabetes.
- The Contact Activation and Kallikrein/Kinin Systems: Pathophysiologic and Physiologic Activities.
- Prolylcarboxypeptidase Independently Activates Plasma Prekallikrein (Fletcher Factor).
- Physiologic activities of the Contact Activation System.
- The thromboprotective effect of Bortezomib is dependent on the transcription factor Kruppel-like factor 2 (KLF2).
- Extracorporeal circulation without bleeding.
- Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2.
- Identification of prolyl carboxypeptidase as an alternative enzyme for processing of Renal angiotensin II using mass spectrometry.
- Angiotensin-(1-7) and Mas decrease Thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and GPVI activation.
- A platelet acquired storage pool disorder associated with tamoxifen therapy.
- Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression.
- Are maternal antiplatelet antibodies a prothrombotic condition leading to miscarriage?
- Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial Thrombosis.
- Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.
- Factor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & Thrombosis.
- Why do we want to know how factor XII levels are modulated?
- Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents.
- Thrombosis in flowing blood.
- AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral Thrombosis.
- The elusive physiologic role of Factor XII.
- Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays Thrombosis.
- Sweet and sticky: diabetic platelets, enhanced reactivity, and cardiovascular risk.
- Complications from vascular disrupting agents and angiogenesis inhibitors: aberrant control of hemostasis and Thrombosis.
- Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.
- Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site.
- Myeloperoxidase interacts with endothelial cell-surface cytokeratin 1 and modulates bradykinin production by the plasma Kallikrein-Kinin system.
- Bradykinin B2 receptor knockout mice are protected from Thrombosis by increased nitric oxide and prostacyclin.
- Homonymous hemianopia caused by occipital lobe infarction in heparin-induced thrombocytopenia and thrombosis Syndrome.
- Platelet aggregation testing in platelet-rich plasma: description of procedures with the aim to develop standards in the field.
- Factor VLeiden inhibits fibrinolysis in vivo.
- The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1.
- Recombinant prolylcarboxypeptidase activates plasma prekallikrein.
- Mapping the interaction between high molecular mass kininogen and the urokinase plasminogen activator receptor.
- The relative priority of prekallikrein and factors XI/XIa assembly on cultured endothelial cells.
- Detection of amide I signals of interfacial proteins in situ using SFG.
- Mechanisms of Arg-Pro-Pro-Gly-Phe inhibition of thrombin.
- The kallikrein-kinin and the renin-angiotensin systems have a multilayered interaction.
- Characterization of molecular defects of Fitzgerald trait and another novel high-molecular-weight kininogen-deficient patient: insights into structural requirements fo...
- Laser-light scattering, a new method for continuous monitoring of platelet activation in circulating fluid.
- A functional thrombin receptor (PAR1) is expressed on bone-derived prostate Cancer cell lines.
- Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator.
- Factor XII interacts with the multiprotein assembly of urokinase plasminogen activator receptor, gC1qR, and cytokeratin 1 on endothelial cell membranes.
- Anti-c5a ameliorates Coagulation/fibrinolytic protein changes in a rat model of sepsis.
- The plasma kallikrein-kinin system counterbalances the renin-angiotensin system.
- Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain.
- Factor IXa inhibition by protease nexin-2/amyloid beta-protein precursor on phospholipid vesicles and cell membranes.
- The carboxyl terminus of bradykinin and amino terminus of the light chain of kininogens comprise an endothelial cell binding domain.
- Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of Coagulation factor IXa.
- Administration of gamma interferon in human subjects decreases plasminogen activation and fibrinolysis without influencing C1 inhibitor.
- Expression of platelet C1 inhibitor.
- Bradykinin regulates the expression of kininogen binding sites on endothelial cells.
- Thrombostatin, a bradykinin metabolite, reduces platelet activation in a model of arterial wall injury.
- Mapping the interaction of bradykinin 1-5 with the exodomain of human protease activated receptor 4.
- Synthesis of novel peptide inhibitors of thrombin-induced platelet activation.
- Ordered adsorption of Coagulation factor XII on negatively charged polymer surfaces probed by sum frequency generation vibrational spectroscopy.
- D-dimer, P-selectin, and microparticles: novel markers to predict Deep venous thrombosis. A pilot study.
- Assembly, activation, and physiologic influence of the plasma kallikrein/kinin system.
- The plasma kallikrein/kinin and renin angiotensin systems in blood pressure regulation in sepsis.
- Assembly and activation of the plasma kallikrein/kinin system: a new interpretation.
- The physiologic basis of assembly and activation of the plasma kallikrein/kinin system.
- Plasma prekallikrein: a risk marker for hypertension and nephropathy in type 1 diabetes.
- Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator.
- Thrombotic microangiopathy in haematopoietic stem cell transplantation: diagnosis and treatment.
- Streptococcal inhibitor of complement-mediated lysis (SIC): an anti-inflammatory virulence determinant.
- Oral thrombostatin FM19 inhibits prostate Cancer.
- Oscar D. Ratnoff: a man for all seasons.
- Von Willebrand factor promoter targets the expression of amyloid beta protein precursor to brain vascular endothelial cells of transgenic mice.
- Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and Disease.
- Use of factor IX complex in warfarin-related intracranial hemorrhage.
- Mechanism of epinephrine-induced platelet aggregation.
- Genetic polymorphism of the alpha 2-adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive...
- Effect of negatively charged activating compounds on inactivation of factor XIIa by Cl inhibitor.
- Dural sinus Thrombosis with abnormalities of protein S and fibrinogen.
- Modulation of the cell membrane expression of the kininogens regulates the rate of bradykinin deLivery to cells.
- Factor XII gene mutation in the Hageman family.
- Factor XII: new life for an old protein.
- A multicenter clinical evaluation of the Clot Signature Analyzer.
- Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo.
- The plasma kallikrein-kinin system: its evolution from contact activation.
- Overexpression of prolylcarboxypeptidase enhances plasma prekallikrein activation on Chinese hamster ovary cells.
- Developing peptide inhibitors to thrombin activation of platelets from bradykinin Analogs.
- Thrombostatin inhibits cyclic flow variations in stenosed canine coronary arteries.
- Conformational changes in low molecular weight kininogen alters its ability to bind to endothelial cells.
- Neonatal Purpura fulminans in association with factor V R506Q mutation.
- Phosphatase 2A participates in interferon-gamma's induced upregulation of C1 inhibitor mRNA expression.
- Recombinant Kunitz protease inhibitory domain of the amyloid beta-protein precursor as an anticoagulant in venovenous extracorporeal circulation in rabbits.
- Activation of the plasma kallikrein/kinin system on endothelial cell membranes.
- Activation of the plasma kallikrein/kinin system on cells: a revised hypothesis.
- Association of the prothrombin G20210A mutation with factor V Leiden in a midwestern American population.
- Protease nexin-2/Amyloid beta-protein precursor regulates factor VIIa and the factor VIIa-tissue factor complex.
- Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases.
- Plasma kallikrein/kinin system: a revised hypothesis for its activation and its physiologic contributions.
- Kininogen-cytokeratin 1 interactions in endothelial cell biology.
- Assembly and activation of HK-PK complex on endothelial cells results in bradykinin liberation and NO formation.
- Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells.
- Factor XI assembly and activation on human umbilical Vein endothelial cells in culture.
- Assembly of high molecular weight kininogen and activation of prekallikrein on cell matrix.
- Hemostatic/fibrinolytic protein changes in C3H/HeN mice infected with Rickettsia conorii--a model for Rocky Mountain spotted fever.
Schools
Virginia Commonwealth University Medical College Of Virginia School Of Medicine
Temple University Hospital
University Of Pennsylvania
Procedures Preformed
- Plasmapheresis
Conditions Treated
- Acute Leukemia
- Anal and Rectal Cancer
- Anemia
- Antiphospholipid Syndrome (APS)
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Pathway X Tiered Hosp/Ind Direct Access OH
- Anthem Blue Cross Blue Shield HMO
- Anthem Blue Cross Blue Shield PPO
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- CareSource
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Cofinity PPO
- Commercial Insurance Company
- CoreSource
- Coventry Health America PPO
- First Health (Coventry Health Care) PPO
- Medicare Advantage PFFS
- Choice Care PPO
- Medical Mutual of Ohio POS
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Mutual of Omaha
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- Regional Top Doctor
- Elected Member
Education
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University of Pennsylvania Health System -
Temple University Hospital -
Virginia Commonwealth University School of Medicine
Hospital
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University Hospitals Case Medical Center
Drug Facts
| NPI NUMBER | 1578583134 | |
| NPPES Provider LastName | SCHMAIER | |
| NPPES Provider FirstName | ALVIN | |
| NPPES Provider ZIPCode | 441061716 | |
| NPPES Provider State | OH | |
| Specialty Description | Hematology | |
| Total Claim Count | 346.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 13.0 | |
| Percent Opioid Claims | 3.76 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1578583134 |
| Last Name Of The Provider | SCHMAIER |
| First Name Of The Provider | ALVIN |
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